Posterior Reversible Encephalopathy Syndrome: Three Ethiopian Hypertensive Patients Presented with Recurrent Seizure: Case Series and Literature Review.

Journal: Ethiopian journal of health sciences

Volume: 29

Issue: 4

Year of Publication: 2020

Affiliated Institutions:  Department of Neurology, College of Health Sciences, Addis Ababa University, Ethiopia.

Abstract summary 

Posterior Reversible Encephalopathy Syndrome (PRES) is a potentially reversible neurological disorder of acute to subacute onset characterized by headache, nausea and vomiting, visual disturbance, seizure and altered mental status. Neuroimaging findings are characteristic, which allow early diagnosis in the appropriate clinical setting and enable to institute appropriate therapy timely.We report 3 adult patients with a history of hypertension presented with recurrent episode of seizure and altered mentation. While all the 3 patients were preliminarily diagnosed with Ischemic stroke, they were subsequently diagnosed with posterior reversible encephalopathy syndrome after neuroimaging revealed the typical features of the syndrome. They were started on antihypertensive and anticonvulsant drugs. On follow-up examination after 3-4 weeks, the patients showed marked clinical and neuro-imaging improvements.Posterior reversible encephalopathy syndrome is a rare condition. The presenting clinical symptoms are non-specific and may mimic other neurological disorders. Therefore, early recognition of classic radiographic features is vital to the diagnosis. Timely diagnosis and treatment of this syndrome is important as the treatment outcome is mostly favorable.

Authors & Co-authors:  Yared Zewde Z Yared Yifru Y

Study Outcome 

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Statistics
Citations :  Hinchey J, Chaves C, Appignani B, et al. A reversible posterior leukoencephalopathy syndrome. N Engl J Med. 1996;334(8):494–500.
Authors :  2
Identifiers
Doi : 10.4314/ejhs.v29i4.14
SSN : 2413-7170
Study Population
Male,Female
Mesh Terms
Adolescent
Other Terms
Hypertension;Posterior Reversible Encephalopathy Syndrome;Seizure;Stroke
Study Design
Case Study,Cross Sectional Study
Study Approach
Country of Study
Ethiopia
Publication Country
Ethiopia