Magnitude of metabolic syndrome and its predictors among patients on second-generation antipsychotic drugs at six psychiatry clinics and mental hospitals, in Addis Ababa, Ethiopia, 2019; Multicenter cross-sectional study.

Journal: Diabetes & metabolic syndrome

Volume: 15

Issue: 4

Year of Publication: 2021

Affiliated Institutions:  Department of Pharmacy, College of Medicine and Health Science, Wollo University, Dessie, Ethiopia, Pobox . Electronic address: getasew.amogne@wu.edu.et. Department of Public Health, Universal Medical and Business College, Addis Ababa, Ethiopia. Electronic address: talemu@yahoo.com. Department of Public Health, Yekatit Hospital Medical College, Addis Ababa, Ethiopia. Electronic address: ttrhas@gmail.com. Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Science, Addis Ababa University, Addis Ababa, Ethiopia. Electronic address: mulubaye@gmail.com.

Abstract summary 

Second-generation antipsychotics are an important component in the management of psychiatric conditions but their use can also lead to weight gain, diabetes, and dyslipidemia. Thus, this study aimed to assess the magnitude of metabolic syndrome and its predictors among patients who were on second-generation antipsychotic drugs at six psychiatry Hospitals, in Addis Ababa, Ethiopia, 2019.This study was conducted using a Multicenter cross-sectional study design. Medical charts of 510 patients on second-generation antipsychotic drugs who were selected by convenience sampling method and complete patients' charts were included in this study. Data was gathered using a checklist from patients' medical charts. To identify the determinants of metabolic syndrome, a logistic regression model was used.From a total of 510 patients' Medical charts on the second-generation antipsychotic drugs, 270 (52.9%) of them were females and 240 (47.1%) were males. The magnitude of metabolic syndrome among patients receiving second-generation antipsychotic drugs was found to be 88 (17.8%). Age, education, family history of cardiovascular disease, and type of second-generation antipsychotic drugs are found to be significantly associated factors with metabolic syndrome.Considerable proportion of patients receiving second-generation antipsychotic medications have metabolic syndrome.

Authors & Co-authors:  Amogne Getasew G Alemu Tadesse T Tadesse Trhas T Mullu Assefa A

Study Outcome 

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Citations : 
Authors :  4
Identifiers
Doi : 10.1016/j.dsx.2021.102187
SSN : 1878-0334
Study Population
Females
Mesh Terms
Adult
Other Terms
Associated factors;Magnitude;Metabolic syndrome;Second-generation antipsychotics
Study Design
Cross Sectional Study
Study Approach
Country of Study
Ethiopia
Publication Country
Netherlands