Abstract summary 

Neurodevelopmental disorders (NDDs) are conditions affecting a child's cognitive, behavioural, and emotional development. Appropriate and validated outcome measures for use in children with NDDs in sub-Saharan Africa are scarce. The aim of this study was to validate the Communication Profile Adapted (CP-A), a measure developed in East Africa to assess caregivers' perception of communication among children with NDDs.We adapted the CP-A for use in Ethiopia, focusing on the communicative mode (CP-A-mode) and function (CP-A-function) scales. The CP-A was administered to a representative sample of caregivers of children with NDDs and clinical controls. We performed an exploratory factor analysis and determined the internal consistency, test-retest reliability, within-scale, known-group, and convergent validity of the identified factors.Our analysis included = 300 participants ( = 139 cases, = 139 clinical controls, = 22 who did not meet criteria for either cases or controls). Within the CP-A-mode, we identified two factors (i.e. and ); the CP-A-function scale was unidimensional. Combining both scales into one summary variable (the CP-A-total) resulted in a scale with excellent internal consistency and test-retest reliability (Cronbach's alpha = 0.97; Kappa = 0.60-0.95, < 0.001; ICC = 0.97, < 0.001). Testing known-group validity, the CP-A-total scores were significantly higher for controls than cases (Δ mean = 33.93, < 0.001). Convergent validity assessment indicated that scores were negatively and moderately correlated with clinical severity ( = -0.25, = 0.04).The CP-A is a valid tool for the assessment of communication among children with NDDs in Ethiopia. It holds promise as a brief, quantitative, and culturally appropriate outcome measure for use in sub-Saharan Africa.

Authors & Co-authors:  Ceccarelli Caterina C Bakolis Ioannis I Tekola Bethlehem B Kinfe Mersha M Borissov Anton A Girma Fikirte F Abdurahman Rehana R Zerihun Tigist T Hanlon Charlotte C Hoekstra Rosa A RA

Study Outcome 

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