Common perinatal mental disorders and post-infancy child development in rural Ethiopia: A population-based cohort study.

Journal: Tropical medicine & international health : TM & IH

Volume: 27

Issue: 3

Year of Publication: 2022

Affiliated Institutions:  Health Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, King's Colleges London, Centre for Global Mental Health, London, UK. Aklilu-Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia. Department of Psychiatry, WHO Collaborating Centre for Mental Health Research and Capacity-Building, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia. Department of Paediatrics and Community Health, Addis Ababa University, Addis Ababa, Ethiopia. Genetic Epidemiology Research Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, Maryland, USA. Department of Psychiatry, University of Oxford, Oxford, UK. Department of Global Health, Institute for Life Course Health Research, Stellenbosch University, Cape Town, South Africa. King's College London, King's Global Health Institute, London, UK.

Abstract summary 

To investigate whether maternal common mental disorders (CMD) in the postnatal period are prospectively associated with child development at 2.5 and 3.5 years in a rural low-income African setting.This study was nested within the C-MaMiE (Child outcomes in relation to Maternal Mental health in Ethiopia) population-based cohort in Butajira, Ethiopia, and conducted from 2005 to 2006. The sample comprised of 496 women who had recently given birth to living, singleton babies with recorded birth weight measurements, who were 15 to 44 years of age, and residing in six rural sub-districts. Postnatal CMD measurements were ascertained 2 months after delivery. Language, cognitive, and motor development were obtained from the child 2.5 and 3.5 years after birth using a locally adapted version of the Bayley Scales of Infant Development (3rd Ed). Maternal CMD symptoms were measured using a locally validated WHO Self-Reporting Questionnaire. A linear mixed-effects regression model was used to analyze the relationship between postnatal CMD and child development.After adjusting for confounders, there was no evidence for an association between postnatal CMD and overall child development or the cognitive sub-domain in the preschool period. There was no evidence of effect modification by levels of social support, socioeconomic status, stunting, or sex of the child.Previous studies from predominantly urban and peri-urban settings in middle-income countries have established a relationship between maternal CMD and child development, which contrasts with the findings from this study. The risk and protective factors for child development may differ in areas characterized by high social adversity and food insecurity. More studies are needed to investigate maternal CMD's impact on child development in low-resource and rural areas.

Authors & Co-authors:  Dunn Julia Alexandra JA Medhin Girmay G Dewey Michael M Alem Atalay A Worku Bogale B Paksarian Diana D Newton Charles R CR Tomlinson Mark M Prince Martin M Hanlon Charlotte C

Study Outcome 

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Statistics
Citations :  Howard LM, Molyneaux E, Dennis CL, Rochat T, Stein A, Milgrom J. Non‐psychotic mental disorders in the perinatal period. The Lancet. 2014;384(9956):1775–88.
Authors :  10
Identifiers
Doi : 10.1111/tmi.13725
SSN : 1365-3156
Study Population
Women
Mesh Terms
Child
Other Terms
child development;child mental health;cohort study;postnatal depression;sub-Saharan Africa
Study Design
Cohort Study,Cross Sectional Study
Study Approach
Country of Study
Ethiopia
Publication Country
England