Psychiatric comorbidity in people with epilepsy in Ethiopia: Systematic review and meta-analysis.

Journal: Epilepsy & behavior : E&B

Volume: 152

Issue: 

Year of Publication: 2024

Affiliated Institutions:  University of Gondar, College of Medicine and Health Science, Department of Psychiatry, Ethiopia. Electronic address: techilotinsae@gmail.com. University of Gondar, College of Medicine and Health Science, Department of Psychiatry, Ethiopia. Electronic address: shumetshegaye@yahoo.com. University of Gondar, College of Medicine and Health Science, Department of Psychiatry, Ethiopia. Electronic address: mamarumelkam@gmail.com. Department of Psychiatry, College of Health Science, Mettu University, Mettu, Ethiopia. Electronic address: tesfayes@gmail.com. University of Gondar, College of Medicine and Health Science, Department of Psychiatry, Ethiopia. Electronic address: girmamedfu@gmail.com. University of Gondar, College of Medicine and Health Science, Department of Psychiatry, Ethiopia. Electronic address: gidru@gmail.co. University of Gondar, College of Medicine and Health Science, Department of Psychiatry, Ethiopia. Electronic address: girumnakie@gmail.com. University of Gondar, College of Medicine and Health Science, Department of Psychiatry, Ethiopia. Electronic address: setegnf@gmail.com. University of Gondar, College of Medicine and Health Science, Department of Psychiatry, Ethiopia. Electronic address: fantaandu@gmail.com. University of Gondar, College of Medicine and Health Science, Department of Psychiatry, Ethiopia. Electronic address: wondale@gmail.com.

Abstract summary 

Psychiatric comorbidity is a double burden among people with epilepsy. Since people with epilepsy are more vulnerable to psychiatric illnesses. So, the implementation of an appropriate intervention to minimize the double burden of comorbidity is very important. Therefore, this systematic review and meta-analysis aimed to assess the prevalence and associated factors of psychiatric comorbidity among people with epilepsy in Ethiopia.This systematic review and meta-analysis followed the Preferred Reporting Item Review and Meta-analysis (PRISMA) guideline. Searching databases were PubMed, PsycINFO, Web of Science, Cochrane Library, Google Scholar, and HINARI.The quality of the included articles was assessed using the Newcastle-Ottawa Scale (NOS). The pooled meta-logistic regression was computed to estimate the pooled prevalence and the risk factors with a 95% CI.The pooled prevalence of psychiatric comorbidity in people with epilepsy was 34.69 % (95 % CI: 29.27, 40.10). Frequent seizures (POR = 2.94: 95 % CI: 1.08, 8.00) and a history of divorce (POR = 2.00: 95 % CI: 1.09, 3.81) were associated factors of psychiatric comorbidity in people with epilepsy.This systematic review and meta-analysis revealed that the pooled prevalence of psychiatric comorbidity among people with epilepsy was found to be higher compared with the general population. Therefore, among people with epilepsy, parallel psychiatric evaluation is very important along with neurological evaluation.

Authors & Co-authors:  Tinsae Techilo T Shumet Shegaye S Melkam Mamaru M Segon Tesfaye T Medfu Takelle Girmaw G Rtbey Gidey G Nakie Girum G Fentahun Setegn S Andualem Fantahun F Getinet Wondale W

Study Outcome 

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Citations : 
Authors :  10
Identifiers
Doi : 10.1016/j.yebeh.2024.109648
SSN : 1525-5069
Study Population
Male,Female
Mesh Terms
Humans
Other Terms
Anxiety;Depression;Epilepsy;Psychiatric comorbidity;Psychological distress
Study Design
Cross Sectional Study
Study Approach
Systemic Review
Country of Study
Ethiopia
Publication Country
United States