Abstract summary 

To explore the relationship between low serum vitamin D levels and comorbidity in Somali women, immigrants to Sweden. Cohort study in a Primary Health Care Center and a University Hospital. Somali women skin type V, n = 114, aged 18-56 years, from latitude 0-10 N, living in Sweden, latitude 57 N > 2 years were compared with women from a population sample, skin type II-III, n = 69, aged 38-56 years, the WHO MONICA study, Gothenburg, Sweden. Serum (S)-25(OH)D, S-parathyroid hormone (PTH), comorbidity and Health-Related Quality of Life (HRQoL) using the Short Form-36 (SF-36) and part of the EQ-5D questionnaires. All calculations were corrected for age. Vitamin D deficiency (S-25(OH)D < 25 nmol/l) was found in 73% of the Somali women and in 1% of the controls ( < .0001). S-PTH was elevated (>6.9 pmol/l) in 26% and 9%, respectively ( < .004). Somali women used less medication, 16% vs. 55%,  < .0001) but more allergy medication, 11% vs. 7% ( = .006), had fewer fractures, 2% vs. 28% ( < .0001) and lower HRQoL in 7 out of 9 scales ( < .05-.001), than native controls. There were no differences in the prevalence of diabetes mellitus, hypothyroidism, positive thyroid peroxidase antibodies, vitamin B12 deficiency, celiac disease or hypertension. Vitamin D deficiency was common in Somali women living in Sweden, 73%, but comorbidity was low. Both mental, and especially physical HRQoL scores were lower in the Somali women. The effects of long-lasting deficiency are unknown. Key points The aim was to explore the relationship between vitamin D deficiency (S-25(OH)D < 25 nmol/l) and comorbidity in immigrants. Vitamin D deficiency was common in Somali women living in Sweden, 73%, but comorbidity of hypothyroidism, diabetes mellitus, hypertension, fractures and use of medications was low. Both mental, and especially physical, Health-Related Quality of Life were lower in the Somali women than in native Swedish women. The effects of long-lasting deficiency are unknown.

Authors & Co-authors:  Demeke Taye T Osmancevic Amra A Gillstedt Martin M Krogstad Anne Lene AL Angesjö Eva E Sinclair Håkan H El-Gawad Gamal Abd GA Krantz Emily E Trimpou Penelope P Landin-Wilhelmsen Kerstin K

Study Outcome 

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