The burden of acute disease in Mahajanga, Madagascar - a 21 month study.

Journal: PloS one

Volume: 10

Issue: 3

Year of Publication: 2016

Affiliated Institutions:  University of Texas Southwestern, Division of Emergency Medicine, Dallas, Texas, United States of America; Department of Emergency Medicine, Maricopa Medical Center, Phoenix, Arizona, United States of America. Centre Hôpitalier Universitaire de Mahajanga, Mahajanga, Madagascar. Muhimbili National Hospital, Emergency Medicine Department, Dar Es Salaam, Tanzania; University of California San Francisco, Emergency Medicine and Global Health Sciences, San Francisco, California, United States of America.

Abstract summary 

Efforts to develop effective and regionally-appropriate emergency care systems in sub-Saharan Africa are hindered by a lack of data on both the burden of disease in the region and on the state of existing care delivery mechanisms. This study describes the burden of acute disease presenting to an emergency unit in Mahajanga, Madagascar.Handwritten patient registries on all emergency department patients presenting between 1 January 2011 and 30 September 2012 were reviewed and data entered into a database. Data included age, sex, diagnosis, and disposition. We classified diagnoses into Clinical Classifications Software (CCS) multi-level categories. The population was 53.5% male, with a median age of 31 years. The five most common presenting conditions were 1) Superficial injury; contusion, 2) Open wounds of head; neck; and trunk, 3) Open wounds of extremities, 4) Intracranial injury, and 5) Unspecified injury and poisoning. Trauma accounted for 48%, Infectious Disease for 15%, Mental Health 6.1%, Noncommunicable 29%, and Neoplasms 1.2%. The acuity seen was high, with an admission rate of 43%. Trauma was the most common reason for admission, representing 19% of admitted patients.This study describes the burden of acute disease at a large referral center in northern Madagascar. The Centre Hôpitalier Universitaire de Mahajanga sees a high volume of acutely ill and injured patients. Similar to other reports from the region, trauma is the most common pathology observed, though infectious disease was responsible for the majority of adult mortality. Typhoid fever other intestinal infections were the most lethal CCS-coded pathologies. By utilizing a widely understood classification system, we are able to highlight contrasts between Mahajanga's acute and overall disease burden as well as make comparisons between this region and the rest of the globe. We hope this study will serve to guide the development of context-appropriate emergency medicine systems in the region.

Authors & Co-authors:  Kannan Vijay C VC Andriamalala Clara N CN Reynolds Teri A TA

Study Outcome 

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Statistics
Citations :  Kobusingye OC, Hyder AA, Bishai D, Joshipura M, Hicks ER, Mock C. Emergency Medical Services In: Jamison DT, Breman JG, Measham AR, Alleyne G, Claeson M, Evans DB, et al., editors. Disease Control Priorities in Developing Countries. 2nd ed. Washington (DC): World Bank; 2006. Available: http://www.ncbi.nlm.nih.gov/books/NBK11744/
Authors :  3
Identifiers
Doi : e0119029
SSN : 1932-6203
Study Population
Male,Female
Mesh Terms
Acute Disease
Other Terms
Study Design
Study Approach
Country of Study
Madagascar
Publication Country
United States