Antepartum depression and anxiety associated with disability in African women: cross-sectional results from the CDS study in Ghana and Côte d'Ivoire.

Journal: PloS one

Volume: 7

Issue: 10

Year of Publication: 2013

Affiliated Institutions:  Department of Child and Adolescent Psychiatry, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Abstract summary 

Common mental disorders, particularly unipolar depressive disorders, rank among the top 5 with respect to the global burden of disease. As a major public health concern, antepartum depression and anxiety not only affects the individual woman, but also her offspring. Data on the prevalence of common mental disorders in pregnant women in sub-Saharan Africa are scarce. We provide results from Ghana and Côte d'Ivoire.We subsequently recruited and screened n = 1030 women in the third trimester of their pregnancy for depressed mood, general anxiety, and perceived disability using the Patient Health Questionnaire depression module (PHQ-9), the 7-item Anxiety Scale (GAD-7), and the World Health Organisation Disability Assessment Schedule II (WHO-DAS 2.0, 12-item version). In addition to estimates of means and prevalence, a hierarchical linear regression model was calculated to determine the influence of antepartum depression and anxiety on disability.In Ghana, 26.6% of women showed substantially depressed mood. In Côte d'Ivoire, this figure was even higher (32.9%). Clear indications for a generalized anxiety disorder were observed in 11.4% and 17.4% of pregnant women, respectively. Comorbidity of both conditions was common, affecting about 7.7% of Ghanaian and 12.6% of Ivorian participants. Pregnant women in both countries reported a high degree of disability regarding everyday activity limitations and participation restrictions. Controlled for country and age, depression and anxiety accounted for 33% of variance in the disability score.Antepartum depression and anxiety were highly prevalent in our sample and contributed substantially to perceived disability. These serious threats to health must be further investigated and more data are needed to comprehensively quantify the problem in sub-Saharan Africa.

Authors & Co-authors:  Bindt Carola C Appiah-Poku John J Te Bonle Marguerite M Schoppen Stefanie S Feldt Torsten T Barkmann Claus C Koffi Mathurin M Baum Jana J Nguah Samuel Blay SB Tagbor Harry H Guo Nan N N'Goran Eliezer E Ehrhardt Stephan S

Study Outcome 

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Statistics
Citations :  World Health Organization (2005) WHO mental health: facing the challenges, building solutions Report from the WHO European Ministerial Conference, Regional Office for Europe Denmark.
Authors :  14
Identifiers
Doi : e48396
SSN : 1932-6203
Study Population
Women
Mesh Terms
Adolescent
Other Terms
Study Design
Study Approach
Country of Study
Ghana
Publication Country
United States