The epidemiology of psychiatric disorders in Africa: a scoping review.

Journal: The lancet. Psychiatry

Volume: 8

Issue: 8

Year of Publication: 2021

Affiliated Institutions:  Program on Forced Migration and Health, Heilbrunn Department of Population and Family Health, Columbia University Mailman School of Public Health, New York, NY, USA. Division of Translational Epidemiology, Department of Psychiatry, New York State Psychiatric Institute, New York, NY, USA. New York Genome Center, New York, NY, USA; Division of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, USA. Center for Psychiatric Genomics, Department of Genetics, University of North Carolina School of Medicine, Chapel Hill, NC, USA. Institute for Genomic Health, SUNY Downstate, Health Science University, Brooklyn, NY, USA. Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK. MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK. Department of Mental Health, Ministry of Health-Mozambique, Maputo, Mozambique. Pathology Department, College of Medicine, University of Malawi, Chichiri, Blantyre, Malawi. Department of Psychiatry, College of Medical Sciences, Ahmadu Bello University, Zaria, Nigeria. Division of Translational Epidemiology, Department of Psychiatry, New York State Psychiatric Institute, New York, NY, USA; Columbia University Vagelos College of Physicians and Surgeons; New York State Psychiatric Institute, New York, NY, USA. Division of Translational Epidemiology, Department of Psychiatry, New York State Psychiatric Institute, New York, NY, USA; Columbia University Vagelos College of Physicians and Surgeons; New York State Psychiatric Institute, New York, NY, USA. Electronic address: myrna.weissman@nyspi.columbia.edu.

Abstract summary 

This scoping review of population-based epidemiological studies was done to provide background information on the prevalences and distribution of psychiatric disorders in Africa for calls to broaden diversity in psychiatric genetic studies. We searched PubMed, EMBASE, and Web of Science to retrieve relevant literature in English, French, and Portuguese from Jan 1, 1984, to Aug 18, 2020. In 36 studies from 12 African countries, the lifetime prevalence ranged from 3·3% to 9·8% for mood disorders, from 5·7% to 15·8% for anxiety disorders, from 3·7% to 13·3% for substance use disorders, and from 1·0% to 4·4% for psychotic disorders. Although the prevalence of mood and anxiety disorders appears to be lower than that observed in research outside the continent, we identified similar distributions by gender, although not by age or urbanicity. This review reveals gaps in epidemiological research on psychiatric disorders and opportunities to leverage existing epidemiological and genetic research within Africa to advance our understanding of psychiatric disorders. Studies that are methodologically comparable but diverse in geographical context are needed to advance psychiatric epidemiology and provide a foundation for understanding environmental risk in genetic studies of diverse populations globally.

Authors & Co-authors:  Greene M Claire MC Yangchen Tenzin T Lehner Thomas T Sullivan Patrick F PF Pato Carlos N CN McIntosh Andrew A Walters James J Gouveia Lidia C LC Msefula Chisomo L CL Fumo Wilza W Sheikh Taiwo L TL Stockton Melissa A MA Wainberg Milton L ML Weissman Myrna M MM

Study Outcome 

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Statistics
Citations :  Peterson RE, Kuchenbaecker K, Walters RK, et al. Genome-wide association studies in ancestrally diverse populations: opportunities, methods, pitfalls, and recommendations. Cell 2019; 179: 589–603.
Authors :  14
Identifiers
Doi : 10.1016/S2215-0366(21)00009-2
SSN : 2215-0374
Study Population
Male,Female
Mesh Terms
Africa
Other Terms
Study Design
Study Approach
Country of Study
Publication Country
England