Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight.

Journal: Nature communications

Volume: 10

Issue: 1

Year of Publication: 2019

Affiliated Institutions:  MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK. The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands. Department of Epidemiology, Geisel School of Medicine at Dartmouth College, Hanover, NH, USA. Epigenetics Group, International Agency for Research on Cancer, Lyon, France. Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway. Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Service, Research Triangle Park, Durham, NC, USA. Department of Translational Research in Psychiatry, Max-Planck-Institute of Psychiatry, Munich, Germany. Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA. HDF Comprehensive Cancer Center, University of California, San Francisco, CA, USA. Department of Biological Sciences, North Carolina State University, Raleigh, NC, USA. Department of Preventive Medicine, University of Southern California, Los Angeles, CA, , USA. Centre de recherche du Centre hospitalier universitaire de Sherbrooke, Sherbrooke, QC, Canada. Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA. Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK. Department of Environmental Health, Rollins School of Public Health at Emory University, Atlanta, GA, USA. University of Groningen, University Medical Center Groningen, Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, Groningen Research Institute for Asthma and COPD, Groningen, The Netherlands. Telethon Kids Institute, University of Western Australia, Perth, Australia. University of Groningen, University Medical Center Groningen, Department of Epidemiology and Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands. Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, UK. Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. Human Development and Health, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK. Helsinki Collegium for Advanced Studies, University of Helsinki, Helsinki, Finland. Department of Biological Psychology, Netherlands Twin Register, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. VITO - Health, Mol, Belgium. Research Unit for Gynaecology and Obstetrics, Department of Clinical Research, University of Southern Denmark, Odense, Denmark. Department of Pediatrics, Division of Respiratory Medicine and Allergology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands. Division of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands. Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, Durham, NC, USA. Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium. Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. School of Oral and Dental Sciences, University of Bristol, Bristol, UK. University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands. Center for Human Health and the Environment, North Carolina State University, Raleigh, NC, USA. ISGlobal, Bacelona Institute for Global Health, Barcelona, Spain. Department of Public Health Sciences, School of Medicine, University of California Davis MIND Institute, Sacramento, CA, USA. Division of Epidemiology, Biostatistics and Environmental Health, School of Public Health, University of Memphis, Memphis, TN, USA. Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands. Medical School, University of Western Australia, Perth, Australia. College of Veterinary Medicine, Michigan State University, East Lansing, MI, USA. Obstetrics and Gynaecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, London, UK. Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland. Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Department of Pediatrics, Division of Neonatology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands. School of Food Sciences and Nutrition, University of Leeds, Leeds, UK. Department of Medical Sciences, University of Turin, Turin, Italy. Children's Environmental Health Laboratory, Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA, USA. Department of Biological Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. The George Institute for Global Health, Nuffield Department of Women's & Reproductive Health, University of Oxford, Oxford, UK. Department of Biochemistry, Université de Sherbrooke, Sherbrooke, QC, Canada. Laboratory of Precision Environmental Biosciences, Columbia University Mailman School of Public Health, New York, NY, USA. Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA. Center for Life Course Health Research, Faculty of Medicine, University of Oulu, , Oulu, Finland. Folkhälsan Institute of Genetics, Helsinki, and Research Programs Unit, Molecular Neurology, University of Helsinki, Helsinki, Finland. HUSLAB and the Department of Clinical Chemistry, University of Helsinki, Helsinki, Finland. LICAMM, School of Medicine, Univeristy of Leeds, Leeds, UK. Center for Epigenetics, Johns Hopkins University School of Medicine, Baltimore, MA, USA. AJ Drexel Autism Institute, Drexel University, Philadelphia, PA, USA. KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Institute for Neuroscience and Disease (LIND), Leuven, Belgium. Department of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA. National Institute for Health and Welfare, Helsinki and Oulu, Oulu, Finland. Department of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, MA, USA. Department of Epidemiology, Colorado School of Public Health, and Department of Pediatrics, University of Colorado School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Centre for Genetic Origins of Health and Disease, School of Biomedical Sciences, University of Western Australia, Perth, Australia. Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA. Department of Medicine, Universite de Sherbrooke, Sherbrooke, QC, Canada. Norwegian Institute of Public Health, Oslo, Norway. Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC, USA. Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA. Department for Non-Communicable Diseases, Norwegian Institute for Public Health, Oslo, Norway. MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK. d.a.Lawlor@bristol.ac.uk. MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK. caroline.relton@bristol.ac.uk. University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands. h.snieder@umcg.nl. The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands. j.felix@erasmusmc.nl.

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