Relationship between Lower Extremity Peripheral Arterial Disease and Mild Cognitive Impairment in Hemodialysis Patients.

Journal: Journal of clinical medicine

Volume: 12

Issue: 6

Year of Publication: 

Affiliated Institutions:  Rehabilitation Unit, Shonan Kamakura General Hospital, Okamoto _, Kamakura -, Japan. Kidney Disease and Transplant Center, Shonan Kamakura General Hospital, Kamakura -, Japan. Department of Community Mental Health and Law, National Institute of Mental Health, National Center of Neurology and Psychiatry, Kodaira -, Japan. School of Allied Health Sciences, Kitasato University, Sagamihara -, Japan. Department of Pathology, University of Mbuji-Mayi, Mbuji-Mayi , Democratic Republic of the Congo.

Abstract summary 

The link between arterial stiffness and mild cognitive impairment (MCI) in patients on hemodialysis (HD) has been receiving increased attention. The purpose of this study was to investigate the relationship between cognitive function and ankle brachial index (ABI) and toe brachial index (TBI) values in patients on hemodialysis. Of the 100 participants (mean age: 67.9 years; average history of hemodialysis: 7.3 years). Of these, 46.0% had MCI. The MoCA-J scores were significantly higher in the ABI ≥ 1.06 group. However, the MoCA-J scores divided into the two groups according to the TBI cutoff value were not significantly different. In a multiple regression model with the MoCA-J scores as the objective variable, the ABI was a significantly associated factor. This study indicates that a low ABI might be associated with MCI.

Authors & Co-authors:  Nishimura Akinori A Hidaka Sumi S Kawaguchi Takayuki T Watanabe Aki A Mochida Yasuhiro Y Ishioka Kunihiro K Mwanatanbwe Milanga M Ohtake Takayasu T Kobayashi Shuzo S

Study Outcome 

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Statistics
Citations :  San A., Hiremagalur B., Muircroft W., Grealish L. Screening of cognitive impairment in the dialysis population: A scoping review. Dement. Geriatr. Cogn. Disord. 2017;44:182–195. doi: 10.1159/000479679.
Authors :  9
Identifiers
Doi : 2145
SSN : 2077-0383
Study Population
Male,Female
Mesh Terms
Other Terms
ankle brachial index;hemodialysis;lower extremity artery disease;mild cognitive impairment;peripheral artery disease;toe brachial index
Study Design
Study Approach
Country of Study
Publication Country
Switzerland