The syndemic effects of mental ill health, household hunger, and intimate partner violence on adherence to antiretroviral therapy among pregnant women living with HIV in Yaoundé, Cameroon.

Journal: PloS one

Volume: 16

Issue: 2

Year of Publication: 2021

Affiliated Institutions:  Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America. Department of Maternal and Child Health, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America. Duke Global Health Institute, Duke University, Durham, North Carolina, United States of America. Consultant, Yaoundé, Cameroon. Catholic Relief Services, N'Djamena, Chad. Catholic Relief Services, Baltimore, Maryland, United States of America.

Abstract summary 

This research advances understanding of interrelationships among three barriers to adherence to antiretroviral therapy (ART) among pregnant women living with HIV (WLWH) in Cameroon: probable common mental disorders (CMD), intimate partner violence (IPV), and hunger.The sample included 220 pregnant WLWH in Cameroon. Multivariable modified Poisson regression was conducted to assess the relationship between IPV, hunger, and CMD on ART adherence.Almost half (44%) of participants recently missed/mistimed an ART dose. Probable CMD was associated with greater risk of missed/mistimed ART dose (aRR 1.5 [95% CI 1.1, 1.9]). Hunger was associated with greater risk of missed/mistimed ART dose among those who reported IPV (aRR 1.9 [95% CI 1.2, 2.8]), but not among those who did not (aRR 0.8 [95% CI 0.2, 2.3]).Suboptimal ART adherence, CMD, and IPV were common among pregnant WLWH in Cameroon. Pregnant WLWH experiencing IPV and hunger may be especially vulnerable to suboptimal ART adherence.

Authors & Co-authors:  Cordoba Evette E Parcesepe Angela M AM Gallis John A JA Headley Jennifer J Soffo Claudian C Tchatchou Berenger B Hembling John J Baumgartner Joy Noel JN

Study Outcome 

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Statistics
Citations :  WHO Guidelines Approved by the Guidelines Review Committee. Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection: Recommendations for a Public Health Approach. Geneva: World Health Organization; 2013.
Authors :  8
Identifiers
Doi : e0246467
SSN : 1932-6203
Study Population
Women
Mesh Terms
Adolescent
Other Terms
Study Design
Study Approach
Country of Study
Cameroon
Publication Country
United States