Neurocognitive testing in West African children 3-6 years of age: Challenges and implications for data analyses.

Journal: Brain research bulletin

Volume: 145

Issue: 

Year of Publication: 2020

Affiliated Institutions:  EHESP, F- Rennes, France; Inserm UMR , Obstetrical, Perinatal and Pediatric Epidemiology Research Team (Epopé), Center for Epidemiology and Statistics Sorbonne Paris Cité, DHU Risks in Pregnancy, Paris Descartes University, Paris, France. Electronic address: florence.bodeau-livinec@ehesp.fr. Columbia University, Mailman School of Public Health and the College of Physicians and Surgeons, NY, USA. Electronic address: lld@cumc.columbia.edu. Institut de Recherche pour le Développement, Mère et enfant face aux infections tropicales, Faculté de Pharmacie de Paris, Université Paris Descartes, Paris, France; The Centre Biomédical des Cordeliers, Université Pierre et Marie Curie, Paris, France; PRES Paris Sorbonne Cité, Université Paris Descartes, Paris, France. Electronic address: zoumenour@yahoo.fr. Université d'Abomey-Calavi, Faculté des Sciences de la Santé, Cotonou, Benin. Electronic address: massougbodjiachille@yahoo.fr. Institut de Recherche pour le Développement, Mère et enfant face aux infections tropicales, Faculté de Pharmacie de Paris, Université Paris Descartes, Paris, France; The Centre Biomédical des Cordeliers, Université Pierre et Marie Curie, Paris, France; PRES Paris Sorbonne Cité, Université Paris Descartes, Paris, France. Electronic address: Michel.cot@ird.fr. Departments of Psychiatry and Neurology & Ophthalmology, Michigan State University, fee Road, Rm , West Fee Hall, East Lansing, MI, , USA; Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA. Electronic address: boivin@msu.edu.

Abstract summary 

When testing African children with developmental and cognitive standardized tests from high-income countries (HIC), investigators are uncertain as to whether to apply the HIC norms for these tests when standardizing a child's raw-score performance on the basis of age. The present study compared the construct validity of both raw and HIC-based standardized scores for the Mullen Scales of Early Learning (MSEL) and the Kaufman Assessment Battery in Children - 2nd edition (KABC-II) for Beninese children in a rural setting from three to six years of age.Seventy-four children 3-4 yrs of age were assessed with the MSEL, and 61 eligible older children (5-6 yrs of age) were assessed with the KABC-II. Assessors spoke the instructions to the children and caregivers for the assessment items in the local language. The developmental quality of the home environment was evaluated with the Caldwell Home Observation for Measurement of the Environment (HOME) inventory, and a material possessions and housing quality checklist was used as a measure of socio-economic status (SES). Children's mothers were given the Raven's Progressive Matrices test (nonverbal cognitive ability), and the Edinburgh Postpartum Depression Scale (EPDS) (emotional wellbeing).For the MSEL, the 4-yr old group performed significantly better than the 3-yr old group on both the raw and standardized score comparisons for all scales. These differences were attenuated when using standardized scores, although the MSEL standardized cognitive composite score was still highly significant between years of age. When comparing 5- to 6-yr olds on KABC-II subtest and global scale performance, comparisons between the raw and standardized mean score performances were much less consistent. Generally, 6-yr olds performed significantly better than 5-yr olds on the raw score comparisons on the KABC-II subtests, but not so for standardized scores. Parent-child interactions assessed through the HOME measure was associated with both raw and standardized MSEL cognitive composite score outcomes on a multiple regression analysis. SES was the only significant predictor for KABC-II raw and standardized outcomes.Standardization using HIC norms was not optimal, resulting in minimal impact to account for age when using the MSEL, and lower scores for oldest children compared with youngest children when using the KABC2. This is likely due to children in Benin drifting away from HIC-based norms with each passing year of age, systematically lowering standardized performance measures. These findings support the importance of having a local comparison group of reference or control children to allow for adjusted (for age, HOME, and SES) raw score comparisons when using western-based tests for developmental and neuropsychological evaluation.

Authors & Co-authors:  Bodeau-Livinec Florence F Davidson Leslie L LL Zoumenou Roméo R Massougbodji Achille A Cot Michel M Boivin Michael J MJ

Study Outcome 

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Statistics
Citations :  Bangirana P, John CC, Idro R, Opoka RO, Byarugaba J, Jurek AM, Boivin MJ. Socioeconomic predictors of cognition in Ugandan children: Implications for community based interventions. PLOS ONE. 2009a;4(11):e7898. doi: 10.1371/journal.pone.0007898.
Authors :  6
Identifiers
Doi : 10.1016/j.brainresbull.2018.04.001
SSN : 1873-2747
Study Population
Mothers
Mesh Terms
Africa, Western
Other Terms
Africa;Child development;HOME scale;Kaufman Assessment Battery for children;Mullen Scales of Early Learning;Neurocognition
Study Design
Study Approach
Country of Study
Benin
Publication Country
United States