Ethnopharmacological importance and medical applications of Myrothamnus flabellifolius Welw. (Myrothamnaceae)-A review.

Journal: Journal of ethnopharmacology

Volume: 252

Issue: 

Year of Publication: 2020

Affiliated Institutions:  IKS Research Group, Department of Pharmacology, Faculty of Health Sciences, University of the Free State, Bloemfontein, , Free State, South Africa; Phytomedicine Unit, Department of Plant Biology and Biotechnology, University of Benin, PMB, , Benin City, Nigeria. University of Science & Technology (UST), Korean Institute of Oriental Medicine, Korean Convergence Medicine Major, Daejeon, Republic of Korea; Herbal Medicine Resources Research Center, Korea Institute of Oriental Medicine, Geonjae-ro, Naju-si, Republic of Korea; Natural Chemotherapeutics Research Institute (NCRI), Ministry of Health, P.O. Box , Kampala, Uganda. University of Science & Technology (UST), Korean Institute of Oriental Medicine, Korean Convergence Medicine Major, Daejeon, Republic of Korea; Herbal Medicine Resources Research Center, Korea Institute of Oriental Medicine, Geonjae-ro, Naju-si, Republic of Korea. Department of Pharmacology, School of Pharmacy, Beijing University of Chinese Medicine, Beijing, People's Republic of China. IKS Research Group, Department of Pharmacology, Faculty of Health Sciences, University of the Free State, Bloemfontein, , Free State, South Africa. Electronic address: matsabisamg@ufs.ac.za.

Abstract summary 

Myrothamnus flabellifolius Welw. (resurrection plant) is a desiccant-tolerant, woody, and shrubby plant. It is popularly used as a local medicinal herbal tea in South Africa, other Southern Africa nations, and Central Africa. M. flabellifolius is used in treating several ailments including epilepsy, mental disorder, cough, pain, stroke, shingles, diabetes, hypertension, wounds, asthma, kidneys and chest ailments.This review focuses on the botanical description, distribution, conservation status, ethnobotany, chemistry and pharmacological properties of M. flabellifolius to spur further research that will promote its sustainable harvesting and commercialization.A literature search on diverse scientific databases, including Google, Google Scholar, Science Direct, PubMed, Scopus, theses, dissertations and ethnobotanical textbooks, were conducted.The conducted search reveals that M. flabellifolius has many traditional uses that can be categorized into infectious diseases, Well-being, respiratory, inflammation, wound and kidney ailments. M. flabellifolius is a natural caffeine-free medicinal herbal tea reported to have antioxidant, anticancer, antiviral, antidiabetic and antimicrobial properties. Toxicological tests on M. flabellifolius were found scarce with gaps in genotoxicological and in vivo studies. Essential oils and isolated compounds were identified from M. flabellifolius with biological activities such as anticancer, antiinflammation, antimicrobial, antiarthritic, antiulcer, antioxidant and antiviral properties.It is envisaged that the current review will add value to more scientific research on M. flabellifolius and enhance/promote the increased interest in the sustainable commercialization of M. flabellifolius herbal tea as well as lead to the validation of unverified ethnobotanical claims.

Authors & Co-authors:  Erhabor Komakech Kang Tang Matsabisa

Study Outcome 

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Statistics
Citations : 
Authors :  5
Identifiers
Doi : 10.1016/j.jep.2020.112576
SSN : 1872-7573
Study Population
Male,Female
Mesh Terms
Animals
Other Terms
Herbal tea;Myrothamnaceae;Myrothamnus flabellifolius;Pharmacological activities;Traditional medicine
Study Design
Study Approach
Country of Study
South Africa
Publication Country
Ireland