Effectiveness of mindful self-compassion therapy on psychopathology symptoms, psychological distress and life expectancy in infertile women treated with in vitro fertilization: a two-arm double-blind parallel randomized controlled trial.

Journal: BMC psychiatry

Volume: 24

Issue: 1

Year of Publication: 2024

Affiliated Institutions:  Department of Psychology, Higher Education Center of Eghlid, Eghlid, Iran. Department of Psychology, Koç University College of Social Sciences and Humanities, Istanbul, Turkey. Hranjbar@ku.edu.tr. Infertility Research Centre, Shiraz University of Medical Sciences, Shiraz, Iran. Department of Social Work and Social Administration, The University of Hong Kong, Hong Kong SAR, China. Institute for Positive Psychology and Education, Australian Catholic University, North Sydney, NSW, Australia. Department of Psychology, Norwegian University of Science and Technology, Dragvoll, Trondheim, Norway. Mojtaba.h.asgarabad@ntnu.no.

Abstract summary 

Infertility is a prominent problem affecting millions of couples worldwide. Recently, there has been a hightened emphasis on elucidating the subtle linkages between infertility treatment leveraging assisted reproductive technology and the complex realm of psychological challenges, as well as efforts in implementation of psychological interventions.The Mindful Self-Compassion (MSC) program seeks to improve self-compassion, compassion for others, mindfulness, and life satisfaction while reducing depression, anxiety, and stress. In the current study, an MSC intervention was performed on infertile women (IW) undergoing in vitro fertilization (IVF) to assess the effectiveness of this intervention in reducing psychological distress and psychopathological symptoms and enhancing life expectancy.Fifty-seven IW undergoing IVF were randomly allocated to two groups: MSC (n = 29) or treatment as usual (TAU; n = 28). Participants in MSC met once a week for two hours for eight weeks and attended a half-day meditation retreat. The Synder's Hope questionnaire and the Revised 90-Symptom Checklist (SCL-90-R) were used as the primary outcome measures. Data were obtained before the intervention, immediately after the intervention, and two months post-intervention. Repeated measures of ANCOVA and paired t-tests in all assessment points were used to compare the MSC and the TAU groups in outcomes.In the MSC group, hopelessness, anger-hostility, anxiety, interpersonal sensitivity difficulties, and depression were significantly reduced compared with the TAU group, and those improvements persisted at the two-month follow-up. Reliable change index revealed that the MSC group's gains were both clinically significant and durable.MSC can facilitate higher life satisfaction and mental well-being for IW undergoing IVF by reducing psychological distress, psychopathological symptoms, and hopelessness. These encouraging findings call for more research into the effectiveness of mindfulness-based therapies in addressing psychological problems among IW undergoing IVF.

Authors & Co-authors:  Sahraian Abdollahpour Ranjbar Namavar Jahromi Cheung Ciarrochi Habibi Asgarabad

Study Outcome 

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Statistics
Citations :  Vander Borght M, Wyns C. Fertility and infertility: definition and epidemiology. Clin Biochem. 2018;62:2–10. doi: 10.1016/j.clinbiochem.2018.03.012.
Authors :  6
Identifiers
Doi : 174
SSN : 1471-244X
Study Population
Women,Female
Mesh Terms
Female
Other Terms
In vitro fertilization;Infertility;Mindfulness-based intervention;Psychological distress;Self-compassion
Study Design
Study Approach
Country of Study
Publication Country
England