Above and Beyond Number of Illnesses: A Two-Sample Replication of Current Approaches to Depressive Symptoms in Multimorbidity.

Journal: Clinical gerontologist

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Affiliated Institutions:  Weill Cornell Medicine, Division of Geriatrics and Palliative Medicine, New York, New York, USA. Psychology, Hunter College and The Graduate Center, City University of New York, New York, New York, USA.

Abstract summary 

To expand current models of depressive symptoms in older adults with multimorbidity (MM) beyond the number of illnesses as a predictor of worsened mental health.Two-sample replication study of adults ≥62 years old with ≥ two chronic illnesses, who completed validated questionnaires assessing depressive symptoms, and disease- and treatment-related stressors. Data were analyzed using hierarchical linear regression.The model of cumulative number of illnesses was worse at explaining variance in depressive symptoms (Sample 1  = .035; Sample 2  = .029), compared to models including disease- and treatment-related stressors (Sample 1  = .37; Sample 2  = .47). Disease-related stressors were the strongest factor associated with depressive symptoms, specifically, poor subjective cognitive function (Sample 1:  = -.202,  = .013; Sample 2:  = -.288,  < .001) and greater somatic symptoms ( = .455,  < .001; Sample 2:  = .355,  < .001).Using the number of illnesses to understand depressive symptoms in MM is a limited approach. Models that move beyond descriptive relationships between MM and depressive symptoms are needed.Providers should consider the role of somatic symptom management in patients with MM and depressive symptoms.

Authors & Co-authors:  Mindlis Revenson

Study Outcome 

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Statistics
Citations : 
Authors :  2
Identifiers
Doi : 10.1080/07317115.2024.2324323
SSN : 1545-2301
Study Population
Male,Female
Mesh Terms
Other Terms
Aging;depressive symptoms;disease burden;multimorbidity;older adults;treatment burden
Study Design
Study Approach
Country of Study
Publication Country
United States