The role of pharmacogenomics in precision mental health care.

Journal: Journal of the American Association of Nurse Practitioners

Volume: 36

Issue: 3

Year of Publication: 2024

Affiliated Institutions:  The Hamilton Group Behavioral Health LLC, Las Vegas, Nevada.

Abstract summary 

Pharmacogenomics is the study of how genes affect a person's response to medications. This science has given rise to the practice of "precision health care," which combines pharmacology (the study of medication) and genomics (the study of genes and their functions) to inform a more personalized approach. Related considerations include which medications to prescribe to different individuals and what doses will have the most therapeutic effects (with the fewest side effects). A case of recalcitrant depression and anxiety (in the context of chronic inflammatory and autoimmune disease) serves as the basis for discussion of psychopharmacogenomics to inform a more effective treatment approach for psychiatric symptoms. A contemporary understanding of neurobiology and neuropathology, enhanced by genetic and genomic information, supports new models for diagnosis and precision treatment of commonly recurring mental health problems.

Authors & Co-authors:  Hamilton

Study Outcome 

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Statistics
Citations :  Amos T., Tandon N., Lefebvre P., Pilon D., Kamstra R., Pivneva I., Greenberg P. (2018). Direct and indirect cost burden and change of employment status in treatment-resistant depression: A matched-cohort study using a U.S. commercial claims database. The Journal of Clinical Psychiatry, 79(2), 17m11725. https://doi.org/10.4088/JCP.17m11725
Authors :  1
Identifiers
Doi : 10.1097/JXX.0000000000000987
SSN : 2327-6924
Study Population
Male,Female
Mesh Terms
Humans
Other Terms
Study Design
Study Approach
Country of Study
Publication Country
United States