Incidence, risk factors and impact of anemia after elective neurosurgery: A retrospective cohort study.

Journal: World neurosurgery: X

Volume: 22

Issue: 

Year of Publication: 

Affiliated Institutions:  Department of Neuroanesthesia and Neurocritical Care, National Institute of Mental Health and Neurosciences Bengaluru, India. Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, India.

Abstract summary 

Anemia after surgery is common and is associated with adverse clinical outcomes. Understanding the incidence and risk factors for postoperative anemia is important to reduce anemia-related complications and blood transfusion. There is lack of data regarding postoperative anemia and its contributing factors in neurosurgery. This study evaluates the incidence and risk factors of postoperative anemia, and its impact on clinical outcomes.This was a single centre, retrospective study of patients who underwent elective neurosurgery over seven months. Data regarding age, gender, body mass index, American Society of Anesthesiologists (ASA) physical status, diagnosis, surgery, preoperative hemoglobin, surgery duration, intraoperative blood loss and red blood cell (RBC) transfusion, dose of tranexamic acid, intraoperative fluid balance, years of surgeon's experience, postoperative hemoglobin, postoperative RBC transfusion, Glasgow Coma Scale (GCS) score at hospital discharge, and duration of postoperative intensive care unit and hospital stay were collected. Logistic regression was used to identify predictors of postoperative anemia.The incidence of postoperative anemia was 11.3% (116/1025). On univariate analysis; age, preoperative hemoglobin, surgery duration, gender, ASA grade, surgery type, and surgeon's experience were associated with postoperative anemia. Lower preoperative hemoglobin (p<0.001) and non-tumor surgery (p<0.001) were predictive of postoperative anemia on multivariate analysis. Postoperative anemia resulted in increased RBC transfusion (p<0.001) and lower GCS score at discharge (p=0.012).Atleast one in ten patients undergoing elective neurosurgery develop postoperative anemia. Lower preoperative hemoglobin and non-tumor surgery predict anemia. Anemia results in increased RBC transfusion and lower discharge GCS score.

Authors & Co-authors:  Giribabu Karan Sriganesh Shukla Devi

Study Outcome 

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Statistics
Citations :  Lawson J.W., Kitchens C.S. Surgery and hemostasis. Curr Opin Hematol. 2015;22(5):420–427.
Authors :  5
Identifiers
Doi : 100289
SSN : 2590-1397
Study Population
Male,Female
Mesh Terms
Other Terms
Blood transfusion;Incidence;Neurosurgery;Outcomes;Postoperative anemia;Risk factors
Study Design
Cohort Study,Cohort Study,Cohort Study,Cohort Study,Cohort Study,Cohort Study
Study Approach
Country of Study
Publication Country
United States