Characteristics and outcomes of youth with functional seizures attending intensive interdisciplinary pain treatment.

Journal: Epilepsy & behavior : E&B

Volume: 153

Issue: 

Year of Publication: 2024

Affiliated Institutions:  Department of Psychiatry & Psychology, Mayo Clinic, First Street SW, Rochester, MN , USA; Department of Pediatrics, Children's Mercy Kansas City, Gillham Road, Kansas City, MO , USA; University of Missouri-Kansas City School of Medicine, Holmes St, Kansas City, MO , USA. Electronic address: jascheurich@cmh.edu. Department of Pediatric & Adolescent Medicine, Mayo Clinic, First Street SW, Rochester, MN , USA. Electronic address: klaas.kelsey@mayo.edu. Department of Psychiatry & Psychology, Mayo Clinic, First Street SW, Rochester, MN , USA. Electronic address: sim.leslie@mayo.edu. Department of Psychiatry & Psychology, Mayo Clinic, First Street SW, Rochester, MN , USA. Electronic address: weiss.karen@mayo.edu. Department of Otolaryngology, Texas Tech University Health Sciences Center, th Street STOP , Lubbock, TX , USA. Electronic address: hannah.case@ttuhsc.edu. Department of Psychiatry & Psychology, Mayo Clinic, First Street SW, Rochester, MN , USA. Electronic address: harbeckweber.cynthia@mayo.edu.

Abstract summary 

Functional seizures (FS) can be debilitating and negatively impact quality of life. Yet intervention research for FS is limited, especially for youth. This study examined clinical characteristics and outcomes of youth with FS (13-23 years) presenting to a pediatric intensive interdisciplinary pain treatment (IIPT) program in the midwestern United States. Sixty youth (mean age = 16.5 years; 83.3 % female) met inclusion criteria. At intake, comorbid chronic pain, somatic symptoms, autonomic dysfunction, eating and weight disturbances, and mental health concerns were common. Despite this high symptom burden, youth with FS reported significant improvements in functioning measured with the Functional Disability Inventory, t(53) = 9.80, p <.001, d = 1.32; depression measured with the Center for Epidemiological Studies - Depression Scale for Children, t(53) = 6.76, p <.001, d = 0.91; anxiety measured with the Spence Children's Anxiety Scale, t(53) = 3.97, p < .001, d = 0.53; and catastrophizing measured with the Pain Catastrophizing Scale for Children, t(53) = 6.44, p <.001, d = 0.86, following completion of the program, suggesting that IIPT may be an effective treatment option for highly disabled and emotionally distressed youth with FS. Future research is needed to continue to refine best practices for youth with FS to reduce suffering and improve outcomes.

Authors & Co-authors:  Scheurich Klaas Sim Weiss Case Harbeck-Weber

Study Outcome 

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Statistics
Citations : 
Authors :  6
Identifiers
Doi : 10.1016/j.yebeh.2024.109689
SSN : 1525-5069
Study Population
Male,Female
Mesh Terms
Humans
Other Terms
Functional neurological disorder;Functional neurological symptom disorder;Functional seizures;Intensive interdisciplinary pain treatment;Pain rehabilitation;Pediatric;Psychogenic nonepileptic seizures
Study Design
Study Approach
Country of Study
Publication Country
United States