Keep in mind sex differences when prescribing psychotropic drugs.

Journal: World journal of psychiatry

Volume: 14

Issue: 2

Year of Publication: 

Affiliated Institutions:  Department of Neurosciences, Fondazione Policlinico Universitario A Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome , Italy. mariannamazza@hotmail.com. Mental Health, NHS, ASL Teramo, Teramo , Italy. Department of Neurosciences, Fondazione Policlinico Universitario A Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome , Italy.

Abstract summary 

Women represent the majority of patients with psychiatric diagnoses and also the largest users of psychotropic drugs. There are inevitable differences in efficacy, side effects and long-term treatment response between men and women. Psychopharmacological research needs to develop adequately powered animal and human trials aimed to consider pharmacokinetics and pharmacodynamics of central nervous system drugs in both male and female subjects. Healthcare professionals have the responsibility to prescribe sex-specific psychopharmacotherapies with a priority to differentiate between men and women in order to minimize adverse drugs reactions, to maximize therapeutic effectiveness and to provide personalized management of care.

Authors & Co-authors:  Mazza De Berardis Marano

Study Outcome 

Source Link: Visit source

Statistics
Citations :  Romanescu M, Buda V, Lombrea A, Andor M, Ledeti I, Suciu M, Danciu C, Dehelean CA, Dehelean L. Sex-Related Differences in Pharmacological Response to CNS Drugs: A Narrative Review. J Pers Med. 2022;12
Authors :  3
Identifiers
Doi : 10.5498/wjp.v14.i2.194
SSN : 2220-3206
Study Population
Men,Male,Women,Female
Mesh Terms
Other Terms
Psychopharmacology;Psychotropic drugs;Sex differences;Women
Study Design
Study Approach
Country of Study
Publication Country
United States