Abstract summary 

Pediatric neurosurgeries carry a considerable risk of intraoperative bleeding and, subsequently, anemia in the post-operative period. Postoperative anemia is often multifactorial with several factors contributing to its occurrence. The present study aims to quantify the incidence of postoperative anemia, identify potential risk factors, and assess the impact of post-operative anemia on clinical outcomes in the pediatric neurosurgery population.This was a single-center and retrospective cohort study which included children <18 years of age undergoing elective neurosurgery. The data were extracted from the electronic and physical patient health records. Post-operative anemia was defined for this study as a hemoglobin value below 10 g/dL at any time up to 3 days after surgery.A total of 300 children were recruited during the study period. The incidence of post-operative anemia after elective pediatric neurosurgery was 21.33%. Children in the post-operative anemia group were younger ( = 0.004), had lower pre-operative hemoglobin values ( < 0.001), belonged to higher American Society of Anesthesiologists (ASA) physical status ( = 0.023), underwent predominantly supratentorial ( = 0.041) and non-tumor surgeries (0.004), and received lesser intraoperative blood transfusion ( = 0.010) compared to no post-operative anemia group. The factors that remained predictive of post-operative anemia on multivariate analysis were ASA physical status ( = 0.018, odds ratio [OR] = 1.94, 95% confidence interval [CI] of 1.12-3.36), pre-operative hemoglobin ( < 0.001, OR = 0.64, 95% CI of 0.50-0.82), and intraoperative transfusion ( = 0.028, OR = 0.45, 95% CI of 0.22-0.92).Optimization of modifiable risk factors is essential to reduce the occurrence of post-operative anemia and improve outcomes in pediatric neurosurgical patients.

Authors & Co-authors:  Naik Nirale Bharadwaj Sangeetha Shukla Kamath

Study Outcome 

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