Childhood adversity is associated with anxiety and depression in older adults: A cumulative risk and latent class analysis.

Journal: Journal of affective disorders

Volume: 354

Issue: 

Year of Publication: 

Affiliated Institutions:  School of Psychology, University of New South Wales, Kensington, NSW, Australia; Neuroscience Research Australia, Randwick, NSW, Australia; Department of Psychology, University of California, Los Angeles, Los Angeles, CA, USA. Electronic address: j.lian@unsw.edu.au. School of Psychology, University of New South Wales, Kensington, NSW, Australia; Neuroscience Research Australia, Randwick, NSW, Australia. Department of Psychology, University of California, Los Angeles, Los Angeles, CA, USA.

Abstract summary 

The long-lasting influence of childhood adversity on mental health is well documented; however empirical research examining how this association extends into older adults is limited. This study operationalises adversity using cumulative risk and latent class analysis (LCA) models to assess how adversity exposure and typologies may predict anxiety and depression in older adults.Data came from the Personality and Total Health (PATH) Through Life Project (N = 2551, age 60-66). Participants retrospectively reported their childhood experiences of domestic adversity on a 17-item scale. Mental health was measured using four validated questionnaires of depression and anxiety.Linear and generalised additive models (GAM) indicated a dose-response relationship, where a greater number of cumulative adversities were associated with poorer scores on all four mental health measures. LCA identified a four-class solution; with high adversity and high parental dysfunction being associated with poorer mental health outcomes while moderate parental dysfunction and low adversity groups scored at healthy levels. Women reported higher overall anxiety than men, but no notable interactions between ACEs and gender were observed. Patterns revealed by LCA were similar to patterns shown by the cumulative risk model.There is a large time gap from childhood to assessment, making our study susceptible to recall bias. Also, our findings were based on cross-sectional data, limiting causal inferences.Childhood adversity had independent and additive contributions to depression and anxiety in older adulthood, and both cumulative risk and person-centred approaches captured this relationship.

Authors & Co-authors:  Lian Kiely Callaghan Anstey

Study Outcome 

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Statistics
Citations : 
Authors :  4
Identifiers
Doi : 10.1016/j.jad.2024.03.016
SSN : 1573-2517
Study Population
Women
Mesh Terms
Other Terms
ACEs;Adverse childhood experiences;Anxiety;Depression;GAM;LCA
Study Design
Study Approach
Country of Study
Publication Country
Netherlands