Does cannabis use substitute for opioids? A preliminary exploratory survey in opioid maintenance patients.

Journal: European archives of psychiatry and clinical neuroscience

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Affiliated Institutions:  Department of Addictive Behavior and Addiction Medicine, Medical Faculty Mannheim, Central Institute of Mental Health, University of Heidelberg, Square J, , Mannheim, Germany. nina.kroeher@googlemail.com. Department of Addictive Behavior and Addiction Medicine, Medical Faculty Mannheim, Central Institute of Mental Health, University of Heidelberg, Square J, , Mannheim, Germany.

Abstract summary 

Various studies showed that people with substance use disorder use cannabis to reduce withdrawal or dose of their main drug. Using a questionnaire about their cannabis use, 118 participants in an opioid maintenance treatment (OMT) in Germany were examined regarding this strategy. 60% reported to use cannabis. Of those, 72% were using cannabis in the suggested way. Cannabis was used to substitute for, e.g., heroin (44.8%) and benzodiazepines (16.4%). We also asked for an estimation of how good cannabis was able to substitute for several substances (in German school grades (1 till 6)); heroin average grade: 2.6 ± 1.49. Besides that we asked about the idea of cannabis as "self-medication", e.g., to reduce pain (47%) and about negative consequences from cannabis use. Our results suggest to consider the use of cannabis by patients in OMT rather as a harm reduction strategy to reduce the intake of more dangerous drugs.

Authors & Co-authors:  Bekier Frischknecht Eidenmueller Grimm Bach Stenger Kiefer Hermann

Study Outcome 

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Citations :  Abrams DI, Couey P, Shade SB, Kelly M, Benowitz NL (2010) Cannabinoid-opioid interaction in chronic pain. Clin Pharmacol Ther 90(6):844–841
Authors :  8
Identifiers
Doi : 10.1007/s00406-023-01718-3
SSN : 1433-8491
Study Population
Male,Female
Mesh Terms
Other Terms
Cannabis;Methadone;OMT;Opioid addiction;Opioid maintenance treatment
Study Design
Study Approach
Country of Study
Publication Country
Germany