The Sensitivity of Limited-Sequence MRI in Identifying Pediatric Cervical Spine Injury: A Western Pediatric Surgery Research Consortium Multicenter Retrospective Cohort Study.

Journal: The journal of trauma and acute care surgery

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Affiliated Institutions:  University of California San Francisco, UCSF Benioff Children's Hospitals, San Francisco, CA. University of Utah Health, Salt Lake City, UT. Children's Hospital Colorado, Aurora, CO. Phoenix Children's Hospital, Phoenix, AZ. Oregon Health & Sciences University, Portland, OR. Children's Hospital Los Angeles, Los Angeles, CA. University of Washington School of Medicine, and Harborview Medical Center, Seattle, WA. Stanford University, Palo Alto, CA. University of California San Diego, San Diego, CA. University of Texas Southwestern, and Children's Medical Center, Dallas, TX.

Abstract summary 

Clinical clearance of a child's cervical spine after trauma is often challenging due to impaired mental status or an unreliable neurologic examination. Magnetic resonance imaging (MRI) is the gold standard for excluding ligamentous injury in children but is constrained by long image acquisition times and frequent need for anesthesia. Limited-sequence MRI (LSMRI) is used in evaluating the evolution of traumatic brain injury and may also be useful for cervical spine clearance while potentially avoiding the need for anesthesia. The purpose of this study was to assess the sensitivity and negative predictive value of LSMRI as compared to gold standard full-sequence MRI as a screening tool to rule out clinically significant ligamentous cervical spine injury.We conducted a ten-center, five-year retrospective cohort study (2017-2021) of all children (0-18y) with a cervical spine MRI after blunt trauma. MRI images were re-reviewed by a study pediatric radiologist at each site to determine if the presence of an injury could be identified on limited sequences alone. Unstable cervical spine injury was determined by study neurosurgeon review at each site.We identified 2,663 children less than 18 years of age who underwent an MRI of the cervical spine with 1,008 injuries detected on full-sequence studies. The sensitivity and negative predictive value of LSMRI were both >99% for detecting any injury and 100% for detecting any unstable injury. Young children (age < 5 years) were more likely to be electively intubated or sedated for cervical spine MRI.LSMRI is reliably detects clinically significant ligamentous injury in children after blunt trauma. To decrease anesthesia use and minimize MRI time, trauma centers should develop LSMRI screening protocols for children without a reliable neurologic exam.2 (Diagnostic Tests or Criteria).

Authors & Co-authors:  Melhado Durand Russell Polukoff Rampton Iyer Acker Koehler Prendergast Stence O'Neill Padilla Jamshidi Vaughn Ronecker Selesner Lofberg Regner Thiessen Sayama Spurrier Ross Liu Chu McNevin Beni Robinson Linnau Buckley Chao Sabapaty Tong Prolo Ignacio Floan Sachs Kruk Gonda Ryan Pandya Koral Braga Auguste Jensen

Study Outcome 

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Statistics
Citations : 
Authors :  44
Identifiers
Doi : 10.1097/TA.0000000000004271
SSN : 2163-0763
Study Population
Male,Female
Mesh Terms
Other Terms
Study Design
Cohort Study
Study Approach
Country of Study
Publication Country
United States