Screening for depression and anxiety in lung cancer patients: A real-world study using GAD-7 and HADS.

Journal: Thoracic cancer

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Affiliated Institutions:  CAMS Key Laboratory of Translational Research on Lung Cancer, State Key Laboratory of Molecular Oncology, Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China. CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China. Boston University, Boston, MA, USA.

Abstract summary 

The psychological well-being of lung cancer patients is critical in-patient care but frequently overlooked.This study, employing a cross-sectional, questionnaire-based design, aimed to elucidate the prevalence of depressive and anxiety symptoms among lung cancer patients and identify associated risk factors. Participants' demographic, medical history, disease stage, and pathology were systematically collected. Psychological assessment was conducted using the general anxiety disorder-7 (GAD-7), patient health questionnaire-9 (PHQ-9), and hospital anxiety and depression scale (HADS). Statistical analyses were performed using SPSS software (version 25.0).Out of 294 distributed questionnaires, 247 lung cancer patients were included in the final analysis, with an average completion time of 9.08 min. Notably, 32.4% exhibited depressive symptoms, while 30% displayed signs of anxiety. A significant correlation was found between both depressive and anxiety symptoms and a history of tobacco and alcohol consumption. Specifically, increased nicotine dependence and greater cumulative tobacco use were linked to higher rates of depressive symptoms, whereas cumulative alcohol consumption was associated with increased risks of anxiety symptoms.The study affirms the feasibility of GAD-7, PHQ-9, and HADS as screening tools for depressive and anxiety symptoms in lung cancer patients. It further highlights tobacco and alcohol consumption as significant risk factors for poor psychological health in this population.

Authors & Co-authors:  Chau Zhou Chen Ren Ma Zhang Duan

Study Outcome 

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Citations :  Mitchell AJ et al. Prevalence of depression, anxiety, and adjustment disorder in oncological, hematological, and palliative‐care settings: a meta‐analysis of 94 interview‐based studies. Lancet Oncol. 2011;12(2):160–174.
Authors :  7
Identifiers
Doi : 10.1111/1759-7714.15287
SSN : 1759-7714
Study Population
Male,Female
Mesh Terms
Other Terms
Psycho‐Oncology;anxiety;depression;lung cancer;psychology
Study Design
Study Approach
Country of Study
Publication Country
Singapore