Regulation of Sacha Inchi protein on fecal metabolism and intestinal microorganisms in mice.

Journal: Frontiers in nutrition

Volume: 11

Issue: 

Year of Publication: 

Affiliated Institutions:  College of Food Science and Technology, Yunnan Agricultural University, Kunming, China. Pu'er Institute of Pu-erh Tea, Pu-er, China. Pu'er Agricultural Science Research Institute, Pu-er, China.

Abstract summary 

With the increasing demand for protein utilization, exploring new protein resources has become a research hotspot. Sacha Inchi Protein (SIP) is a high-quality plant protein extracted from Sacha Inchi meal. This study aimed to investigate the impact of SIP on mouse metabolomics and gut microbiota diversity and explore the underlying pathways responsible for its health benefits.In this study, the structural composition of SIP was investigated, and the effects of SIP on fecal metabolomics and intestinal microorganisms in mice were explored by LC-MS metabolomics technology analysis and 16S rRNA gene sequencing.The results showed that SIP was rich in amino acids, with the highest Manuscript Click here to view linked References content of arginine, which accounted for 22.98% of the total amino acid content; the potential fecal metabolites of mice in the SIP group involved lipid metabolism, sphingolipid metabolism, arginine biosynthesis, and amino acid metabolism; SIP altered the microbial composition of the cecum in mice, decreased the / value, and It decreased the abundance of the harmful intestinal bacteria and , and increased the abundance of the beneficial intestinal bacteria .In conclusion, SIP is a high-quality plant protein with great potential for development in lipid-lowering, intestinal health, and mental illness, providing valuable clues for further research on its health-promoting mechanisms.

Authors & Co-authors:  Wu Gong Lin Huang Mu Wang Sheng Zhao

Study Outcome 

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Statistics
Citations :  Wu G, Fanzo J, Miller DD, Pingali P, Post MJ. Production and supply of high-quality food protein for human consumption: sustainability, challenges, and innovations. Ann N Y Acad Sci. (2015) 1321:1–19. doi: 10.1111/nyas.12500, PMID:
Authors :  8
Identifiers
Doi : 1354486
SSN : 2296-861X
Study Population
Male,Female
Mesh Terms
Other Terms
Sacha Inchi protein;amino acid composition;fecal metabolism;gut microbiota;high-quality protein
Study Design
Study Approach
Country of Study
Publication Country
Switzerland