Confounding by Indication, Confounding Variables, Covariates, and Independent Variables: Knowing What These Terms Mean and When to Use Which Term.

Journal: Indian journal of psychological medicine

Volume: 46

Issue: 1

Year of Publication: 

Affiliated Institutions:  Dept. of Clinical Psychopharmacology and Neurotoxicology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.

Abstract summary 

The terms , and are often imprecisely used in the context of regression. Independent variables are the full set of variables whose influence on the outcome is studied. Covariates are the independent variables that are included not because they are of interest but because their influence on the outcome can be adjusted for, leaving a more precise understanding of how the single remaining independent variable influences the outcome. Confounding variables are variables that are associated with both independent variables and outcomes; so, the relationship identified between independent variables and outcomes may be due to the confounding variable rather than to the independent variable. Potential confounders should be identified, measured, and adjusted for in regression, just as other covariates are. Confounding by indication occurs when the presence of the independent variable is driven by the confounding variable. Confounding by indication is a special kind of confounding; a confounding variable is a special kind of covariate; and a covariate is a special kind of independent variable in regression analysis. These terms and concepts are explained with the help of examples.

Authors & Co-authors:  Andrade

Study Outcome 

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Statistics
Citations :  Andrade C. A student’s guide to the classification and operationalization of variables in the conceptualization and design of a clinical study: Part 1. Indian J Psychol Med, 2021;43(2): 177–179.
Authors :  1
Identifiers
Doi : 10.1177/02537176241227586
SSN : 0253-7176
Study Population
Male,Female
Mesh Terms
Other Terms
Independent variables;confounding by indication;confounding variables;covariates;predictor variable;regression
Study Design
Study Approach
Country of Study
Publication Country
United States