[Associations between components of metabolic syndrome and cognitive impairment in patients with schizophrenia].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova

Volume: 124

Issue: 3

Year of Publication: 2024

Affiliated Institutions:  Mental Health Research Institute - Tomsk National Research Medical Center, Russian Academy of Science, Tomsk, Russia.

Abstract summary 

To study the relationship between the individual components of the metabolic syndrome and cognitive dysfunction in patients with schizophrenia.A total of 133 patients with schizophrenia were examined. To assess cognitive functioning, the Brief Assessment of Cognition in Schizophrenia (BACS) was used. The components of the metabolic syndrome were determined in accordance with the criteria of the International Diabetes Federation.Hyperglycemia in patients with schizophrenia led to a decrease in cognitive functioning in two domains: verbal fluency (β=-10.67; =0.019) and attention stability (β=-9.519; =0.043). Abdominal obesity was associated with lower indicators of executive functions (β=-8.856; =0.026).It is assumed that drug treatment of some components of the metabolic syndrome may affect cognitive functions in patients with schizophrenia.

Authors & Co-authors:  Kornetova Galkin Mednova Tsiguntsev Boiko Kornetov Ivanova Bokhan

Study Outcome 

Source Link: Visit source

Statistics
Citations : 
Authors :  8
Identifiers
Doi : 10.17116/jnevro202412403182
SSN : 1997-7298
Study Population
Male,Female
Mesh Terms
Humans
Other Terms
abdominal obesity;cognitive impairment;dyslipidemia;hyperglycemia;hypertension;metabolic syndrome;schizophrenia
Study Design
Study Approach
Country of Study
Publication Country
Russia (Federation)