Probiotics Supplementation during Pregnancy: Can They Exert Potential Beneficial Effects against Adverse Pregnancy Outcomes beyond Gestational Diabetes Mellitus?

Journal: Biology

Volume: 13

Issue: 3

Year of Publication: 

Affiliated Institutions:  Department of Food Science and Nutrition, School of the Environment, University of the Aegean, Lemnos, Greece. Department of Nutritional Sciences and Dietetics, Faculty of Health Sciences, International Hellenic University, Thessaloniki, Greece. Faculty of Medicine, University of Thessaly, Larissa, Greece. Department of Biomedical Science, International Hellenic University, Thessaloniki, Greece. Department of Nutrition and Dietetics, School of Physical Education, Sport Science and Dietetics, University of Thessaly, Trikala, Greece.

Abstract summary 

Probiotics, as supplements or food ingredients, are considered to exert promising healthy effects when administered in adequate quantity. Probiotics' healthy effects are related with the prevention of many diseases, as well as decreasing symptom severity. Currently, the most available data concerning their potential health effects are associated with metabolic disorders, including gestational diabetes mellitus. There is also clinical evidence supporting that they may exert beneficial effects against diverse adverse pregnancy outcomes. The purpose of the current narrative study is to extensively review and analyze the current existing clinical studies concerning the probable positive impacts of probiotics supplementation during pregnancy as a protective agent against adverse pregnancy outcomes beyond gestational diabetes mellitus.a comprehensive and thorough literature search was conducted in the most precise scientific databases, such as PubMed, Scopus, and Web of Sciences, utilizing efficient, representative, and appropriate keywords.in the last few years, recent research has been conducted concerning the potential beneficial effects against several adverse pregnancy outcomes such as lipid metabolism dysregulation, gestational hypertensive disorders, preterm birth, excessive gestational weight gain, caesarean risk section, vaginal microbiota impairment, mental health disturbances, and others.up to the present day, there is only preliminary clinical data and not conclusive results for probiotics' healthy effects during pregnancy, and it remains questionable whether they could be used as supplementary treatment against adverse pregnancy outcomes beyond gestational diabetes mellitus.

Authors & Co-authors:  Poulios Pavlidou Papadopoulou Rempetsioti Migdanis Mentzelou Chatzidimitriou Migdanis Androutsos Giaginis

Study Outcome 

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Statistics
Citations :  Latif A., Shehzad A., Niazi S., Zahid A., Ashraf W., Iqbal M.W., Rehman A., Riaz T., Aadil R.M., Khan I.M., et al. Probiotics: Mechanism of action, health benefits and their application in food industries. Front. Microbiol. 2023;14:1216674. doi: 10.3389/fmicb.2023.1216674.
Authors :  10
Identifiers
Doi : 158
SSN : 2079-7737
Study Population
Male,Female
Mesh Terms
Other Terms
adverse pregnancy outcomes;functional properties;health claims;pregnancy;probiotics;supplementation
Study Design
Narrative Study
Study Approach
Country of Study
Publication Country
Switzerland