Scaling up cervical cancer prevention in Western Kenya: Treatment access following a community-based HPV testing approach.

Journal: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Volume: 152

Issue: 1

Year of Publication: 2021

Affiliated Institutions:  University of California, San Francisco, CA, USA. Kenya Medical Research Institute, Nairobi, Kenya. Duke University, Durham, NC, USA.

Abstract summary 

To evaluate access to treatment after community-based HPV testing as testing within screen-and-treat programs has the potential to lower mortality from cervical cancer in low-resource settings.A prospective cohort study was conducted in western Kenya in 2018. Women aged 25-65 years underwent HPV self-testing. HPV-positive women were referred for cryotherapy. Participant data were obtained from questionnaires during screening and treatment. The proportion successfully accessing treatment and variables associated with successful treatment was determined.Of the 750 women included, 140 (18.6%) tested positive for HPV. Of them, 135 were notified of their results, of whom 77 (59.2%) sought treatment and 73 (52.1%) received cryotherapy. Women who received treatment had a shorter time from screening to result notification (median 92 days, interquartile range [IQR] 84-104) compared to those who did not (97 days, IQR 89-106; P=0.061). In adjusted analyses, women with a history of cervical cancer screening (odds ratio [OR] 11, 95% confidence interval [CI] 1.42-85.20) and those electing result notification through a home visit (OR 4, 95% CI 1.23-14.17) were significantly more likely to acquire treatment at follow-up.Linkage to treatment after community-based HPV screening in this population was low, highlighting the need for strategies aimed at strengthening treatment linkage in similar settings.

Authors & Co-authors:  Mungo Ibrahim Bukusi Truong Cohen Huchko

Study Outcome 

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Statistics
Citations :  Bray F, Ferlay J, Soerjomataram I, Siegel R, Torre L, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA A J Clin. 2018;00(00):1–31.
Authors :  6
Identifiers
Doi : 10.1002/ijgo.13171
SSN : 1879-3479
Study Population
Women
Mesh Terms
Adult
Other Terms
Cervical cancer prevention;Cervical cancer screening;Global women's health;HPV screening;Low-income countries;See-and-treat
Study Design
Cohort Study
Study Approach
Country of Study
Kenya
Publication Country
United States