The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990-2019: Findings from the Global Burden of Disease Study 2019.

Journal: The Lancet regional health. Europe

Volume: 16

Issue: 

Year of Publication: 

Affiliated Institutions:  Outpatient and Inpatient Care Service, Central Health Directorate, Region Friuli Venezia Giulia, Italy. Centre for Disease Burden, Norwegian Institute of Public Health, Bergen, Norway. Department of Global Public Health, Karolinska Institute, Stockholm, Sweden. Department of Cardiovascular, Endocrine-metabolic Diseases and Aging, National Institute of Health, Rome, Italy. Department of Mental Health, AUSL Romagna, Ravenna, Italy. Department of Public Health, Aarhus University, Aarhus, Denmark. Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy. Institute for Health Metrics and Evaluation, Department of Health Metrics Sciences, University of Washington, Seattle, WA, USA. Department of Mental Health & Drug Abuse, AUSL Modena, Modena, Italy. Department of Primary Care and Public Health, University of East Anglia, Norwich, UK. Department of Internal Medicine, Catholic University of Rome, Rome, Italy. Cardiology Department Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. Department of Statistics and Econometrics Bucharest Carol Davila University of Economic Studies, Bucharest, Romania. CIBERSAM, Institute of Health Carlos III, Madrid, Spain. Department of Hypertension, Medical University of Lodz, Lodz, Poland. Heidelberg Institute of Global Health (HIGH), Heidelberg University, Heidelberg, Germany. Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy. Department of Social and Clinical Pharmacy, Charles University, Hradec Kralova, Czech Republic. Research Unit on Applied Molecular Biosciences (UCIBIO), University of Porto, Porto, Portugal. Institute of Applied Health Research, University of Birmingham, Birmingham, UK. Faculty of Medical Sciences, University of the West Indies, St Augustine, Trinidad and Tobago. Department of Chemical Sciences, University of Porto, Porto, Portugal. Department of Medicine (Prof N Cruz-Martins PhD), University of Porto, Porto, Portugal. Faculty of Life Sciences and Medicine, King's College London, London, UK. National Centre for AIDS and STD Control, Save the Children, Kathmandu, Nepal. Laboratory of Toxicology, University of Porto, Porto, Portugal. Epidemiology and Medical Statistics, University of Ibadan, Ibadan, Nigeria. Associated Laboratory for Green Chemistry (LAQV), University of Porto, Porto, Portugal. Research Center on Public Health, University of Milan Bicocca, Monza, Italy. Institute of Public Health, Charité Universitätsmedizin Berlin (Charité Medical University Berlin), Berlin, Germany. Health Services Management Training Centre, Semmelweis University, Budapest, Hungary. Department of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Italy. Department of Public Health, Erasmus University Medical Center, Rotterdam, Netherlands. Research Unit, University of Barcelona, Barcelona, Spain. Department of Pharmacy, University of Huddersfield, Huddersfield, UK. Department of Primary Care and Mental Health, University of Liverpool, Liverpool, UK. Department of Legal Medicine and Bioethics, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. Department of Public Health, University of Naples Federico II, Naples, Italy. Functional Neurosurgery Research Center, Shahid Beheshti University of Medical Sciences, Tehram, Iran. Institute of Molecular and Clinical Ophthalmology Basel, Basel, Switzerland. Department of Family Medicine and Public Health, University of Opole, Opole, Poland. MRC/CSO Social and Public Health Sciences Unit, University of Glasgow, Glasgow, UK. Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden. Family Medicine Department, United Arab Emirates University, Al Ain, United Arab Emirates. School of Health Sciences, Kristiania University College, Oslo, Norway. Department of Nursing and Health Promotion, Oslo Metropolitan University, Oslo, Norway. Department of Epidemiology and Public Health University College London, London, UK. Health System and Population Studies Divisions, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh. Biomedical Research Networking Center for Mental Health Network (CIBERSAM), San Juan de Dios Sanitary Park, Sant Boi de Llobregat, Spain. Division of Psychology and Language Sciences, University College London, London, UK. Department of Public Health, University of Helsinki, Helsinki, Finland. Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany. Clinical and Experimental Medicine, University of Catania, Catania, Italy. Department of Health Sciences, University of Leicester, Leicester, UK. National Center for Disease Prevention and Health Promotion, Istituto Superiore di Sanità - Italian National Insitute of Health, Rome, Italy. UCD Centre for Disability Studies, University College Dublin, Dublin, Ireland. Laboratory for Process Engineering, Environment, Biotechnology and Energy (LEPABE) University of Porto, Porto, Portugal. Psychiatry Department, Hospital Universitario Doctor Peset, Valencia, Spain. Health Policy Research Public Health Foundation of India, Gurugram, India. Queensland Brain Institute, School of Public Health, The University of Queensland, Brisbane, QLD, Australia. Department of Healthcare, University of Vlora, Vlora city, Albania. University Research Institute, National and Kapodistrian University of Athens, Athens, Greece. Clinical Microbiology and Parasitology Unit, Dr. Zora Profozic Polyclinic, Zagreb, Croatia. Center for Innovation in Medical Education, Pomeranian Medical University, Szczecin, Poland. Department of Statistics and Econometrics Bucharest University of Economic Studies, Bucharest, Romania. Department of Medical Sciences IRCCS Casa Sollievo della Sofferenza General Hospital, San Giovanni Rotondo, Italy. Health Systems and Policy Research Unit, Ahmadu Bello University, Zaria, Nigeria. Department of Surgery, General University Hospital of Patras, Patras, Greece. Institute of Epidemiology and Medical Biometry Ulm University, Ulm, Germany. Department of General Surgery Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. Department of Anatomy and Embryology Romania, Bucharest, Romania. Department of Pediatrics, National Hospital, Abuja, Nigeria. National School of Public Health Institute of Health Carlos III, Madrid, Spain. Privatpraxis, Heidelberg, Germany. Vision and Eye Research Institute, Anglia Ruskin University, Cambridge, UK. Global Health Governance Programme, University of Edinburgh, Edinburgh, UK. Department of Chemistry, University of Porto, Porto, Portugal. Institute of Infection and Immunity, St George's University of London, London, UK. University Medical Center Groningen, School of Economics and Business University of Groningen, Groningen, Netherlands. WHO Collaborating Centre for Public Health Education and Training Imperial College London, London, UK. Department of Primary Care and Public Health, Imperial College London, London, UK. Clinical and Epidemiological Research in Primary Care (GICEAP), Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Cordoba, Spain. Clinical Epidemiology and Public Health Research Unit, Burlo Garofolo Institute for Maternal and Child Health, Trieste, Italy. Department of Psychosocial Science University of Bergen, Bergen, Norway. Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy. Swiss Research Institute for Public Health and Addiction University of Zürich, Zurich, Switzerland. Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE) University of Groningen, Groningen, Netherlands. Finnish Institute of Occupational Health, Helsinki, Finland. London Institute for Healthcare Engineering, King's College London, London, UK. Department of Psychology, Reykjavik University, Reykjavik, Iceland. Department of Biological Sciences, University of Porto, Porto, Portugal. Surgery, "Sf. Pantelimon" Emergency Clinical Hospital Bucharest, Bucharest, Romania. Faculty of Health and Public Administration, Semmelweis University, Budapest, Hungary. Department of Medicine, University of Valencia, Valencia, Spain. Psychiatry and Medical Psychology Department, University of Lisbon, Lisbon, Portugal. Department of Pathology and Legal Medicine, University of São Paulo, Ribeirão Preto, Brazil. UKK Institute, Tampere, Finland. Department of Medical and Surgical Sciences and Advanced Technologies, University of Catania, Catania, Italy. UCL Great Ormond Street Institute of Child Health, University College London, London, UK. Demographic Change and Aging Research Area, Federal Institute for Population Research, Wiesbaden, Germany. Institute of Health and Society, University of Oslo, Oslo, Norway. Institute for Health Metrics and Evaluation, Department of Health Metrics Sciences, School of Medicine, University of Washington, Seattle, WA, USA.

Abstract summary 

Mental health is a public health issue for European young people, with great heterogeneity in resource allocation. Representative population-based studies are needed. The Global Burden of Disease (GBD) Study 2019 provides internationally comparable information on trends in the health status of populations and changes in the leading causes of disease burden over time.Prevalence, incidence, Years Lived with Disability (YLDs) and Years of Life Lost (YLLs) from mental disorders (MDs), substance use disorders (SUDs) and self-harm were estimated for young people aged 10-24 years in 31 European countries. Rates per 100,000 population, percentage changes in 1990-2019, 95% Uncertainty Intervals (UIs), and correlations with Sociodemographic Index (SDI), were estimated.In 2019, rates per 100,000 population were 16,983 (95% UI 12,823 - 21,630) for MDs, 3,891 (3,020 - 4,905) for SUDs, and 89·1 (63·8 - 123·1) for self-harm. In terms of disability, anxiety contributed to 647·3 (432-912·3) YLDs, while in terms of premature death, self-harm contributed to 319·6 (248·9-412·8) YLLs, per 100,000 population. Over the 30 years studied, YLDs increased in eating disorders (14·9%;9·4-20·1) and drug use disorders (16·9%;8·9-26·3), and decreased in idiopathic developmental intellectual disability (-29·1%;23·8-38·5). YLLs decreased in self-harm (-27·9%;38·3-18·7). Variations were found by sex, age-group and country. The burden of SUDs and self-harm was higher in countries with lower SDI, MDs were associated with SUDs.Mental health conditions represent an important burden among young people living in Europe. National policies should strengthen mental health, with a specific focus on young people.The Bill and Melinda Gates Foundation.

Authors & Co-authors:  Castelpietra Knudsen Agardh Armocida Beghi Iburg Logroscino Ma Starace Steel Addolorato Andrei Andrei Ayuso-Mateos Banach Bärnighausen Barone-Adesi Bhagavathula Carvalho Carvalho Chandan Chattu Couto Cruz-Martins Dargan Deuba da Silva Fagbamigbe Fernandes Ferrara Fischer Gaal Gialluisi Haagsma Haro Hasan Hasan Hostiuc Iacoviello Iavicoli Jamshidi Jonas Joo Jozwiak Katikireddi Kauppila Khan Kisa Kisa Kivimäki Koly Koyanagi Kumar Lallukka Langguth Ledda Lee Lega Linehan Loureiro Madureira-Carvalho Martinez-Raga Mathur McGrath Mechili Mentis Mestrovic Miazgowski Mirica Mirijello Moazen Mohammed Mulita Nagel Negoi Negoi Nwatah Padron-Monedero Panda-Jonas Pardhan Pasovic Patel Petcu Pinheiro Pollok Postma Rawaf Rawaf Romero-Rodríguez Ronfani Sagoe Sanmarchi Schaub Sharew Shiri Shokraneh Sigfusdottir Silva Silva Socea Szócska Tabarés-Seisdedos Torrado Tovani-Palone Vasankari Veroux Viner Werdecker Winkler Hay Ferrari Naghavi Allebeck Monasta

Study Outcome 

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Statistics
Citations :  Reiner RC, Jr., Olsen HE, Ikeda CT, et al. Diseases, Injuries, and Risk Factors in Child and Adolescent Health, 1990 to 2017: findings From the Global Burden of Diseases, Injuries, and Risk Factors 2017 Study. JAMA pediatrics. 2019;173(6)
Authors :  114
Identifiers
Doi : 100341
SSN : 2666-7762
Study Population
Male,Female
Mesh Terms
Other Terms
Europe;Mental disorders;Mental health;Self-harm;Substance use;Young people
Study Design
Study Approach
Country of Study
Kenya
Publication Country
England