AUTHOR'S PROFILE

Medland Sarah E SE

Publications (33)

Genomics yields biological and phenotypic insights into bipolar disorder.

Journal: Nature

Publication Year: 

Authors & Co-authors:  O'Connell Kevin S KS Koromina Maria M van der Veen Tracey T Boltz Toni T David Friederike S FS Yang Jessica Mei Kay JMK Lin Keng-Han KH Wang Xin X Coleman Jonathan R I JRI Mitchell Brittany L BL

Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries.

Journal: Nature genetics

Publication Year: 

Authors & Co-authors:  García-Marín Luis M LM Campos Adrian I AI Diaz-Torres Santiago S Rabinowitz Jill A JA Ceja Zuriel Z Mitchell Brittany L BL Grasby Katrina L KL Thorp Jackson G JG Agartz Ingrid I Alhusaini Saud S

Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries.

Journal: medRxiv : the preprint server for health sciences

Publication Year: 

Authors & Co-authors:  García-Marín Luis M LM Campos Adrian I AI Diaz-Torres Santiago S Rabinowitz Jill A JA Ceja Zuriel Z Mitchell Brittany L BL Grasby Katrina L KL Thorp Jackson G JG Agartz Ingrid I Alhusaini Saud S

A blended genome and exome sequencing method captures genetic variation in an unbiased, high-quality, and cost-effective manner.

Journal: bioRxiv : the preprint server for biology

Publication Year: 

Authors & Co-authors:  Boltz Toni A TA Chu Benjamin B BB Liao Calwing C Sealock Julia M JM Ye Robert R Majara Lerato L Fu Jack M JM Service Susan S Zhan Lingyu L Medland Sarah E SE

Genome-wide association study identifies 30 obsessive-compulsive disorder associated loci.

Journal: medRxiv : the preprint server for health sciences

Publication Year: 

Authors & Co-authors:  Strom Nora I NI Gerring Zachary F ZF Galimberti Marco M Yu Dongmei D Halvorsen Matthew W MW Abdellaoui Abdel A Rodriguez-Fontenla Cristina C Sealock Julia M JM Bigdeli Tim T Coleman Jonathan R JR

Genetic variants for head size share genes and pathways with cancer.

Journal: Cell reports. Medicine

Publication Year: 

Authors & Co-authors:  Knol Maria J MJ Poot Raymond A RA Evans Tavia E TE Satizabal Claudia L CL Mishra Aniket A Sargurupremraj Muralidharan M van der Auwera Sandra S Duperron Marie-Gabrielle MG Jian Xueqiu X Hostettler Isabel C IC

Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder.

Journal: Nature genetics

Publication Year: 

Authors & Co-authors:  Nievergelt Caroline M CM Maihofer Adam X AX Atkinson Elizabeth G EG Chen Chia-Yen CY Choi Karmel W KW Coleman Jonathan R I JRI Daskalakis Nikolaos P NP Duncan Laramie E LE Polimanti Renato R Aaronson Cindy C

ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide.

Journal: NeuroImage

Publication Year: 2018

Authors & Co-authors:  Thompson Paul M PM Andreassen Ole A OA Arias-Vasquez Alejandro A Bearden Carrie E CE Boedhoe Premika S PS Brouwer Rachel M RM Buckner Randy L RL Buitelaar Jan K JK Bulayeva Kazima B KB Cannon Dara M DM

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Journal: Nature genetics

Publication Year: 2019

Authors & Co-authors:  Turcot Valérie V Lu Yingchang Y Highland Heather M HM Schurmann Claudia C Justice Anne E AE Fine Rebecca S RS Bradfield Jonathan P JP Esko Tõnu T Giri Ayush A Graff Mariaelisa M

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Journal: Nature genetics

Publication Year: 

Authors & Co-authors:  Turcot Valérie V Lu Yingchang Y Highland Heather M HM Schurmann Claudia C Justice Anne E AE Fine Rebecca S RS Bradfield Jonathan P JP Esko Tõnu T Giri Ayush A Graff Mariaelisa M

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Journal: Nature genetics

Publication Year: 

Authors & Co-authors:  Turcot Valérie V Lu Yingchang Y Highland Heather M HM Schurmann Claudia C Justice Anne E AE Fine Rebecca S RS Bradfield Jonathan P JP Esko Tõnu T Giri Ayush A Graff Mariaelisa M

Significant concordance of genetic variation that increases both the risk for obsessive-compulsive disorder and the volumes of the nucleus accumbens and putamen.

Journal: The British journal of psychiatry : the journal of mental science

Publication Year: 2019

Authors & Co-authors:  Hibar Derrek P DP Cheung Joshua W JW Medland Sarah E SE Mufford Mary S MS Jahanshad Neda N Dalvie Shareefa S Ramesar Raj R Stewart Evelyn E van den Heuvel Odile A OA Pauls David L DL

Concordance of genetic variation that increases risk for anxiety disorders and posttraumatic stress disorders and that influences their underlying neurocircuitry.

Journal: Journal of affective disorders

Publication Year: 2019

Authors & Co-authors:  van der Merwe Celia C Jahanshad Neda N Cheung Josh W JW Mufford Mary M Groenewold Nynke A NA Koen Nastassja N Ramesar Rajkumar R Dalvie Shareefa S Knowles James A JA

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Journal: Nature genetics

Publication Year: 

Authors & Co-authors:  Turcot Valérie V Lu Yingchang Y Highland Heather M HM Schurmann Claudia C Justice Anne E AE Fine Rebecca S RS Bradfield Jonathan P JP Esko Tõnu T Giri Ayush A Graff Mariaelisa M

Mapping Cortical and Subcortical Asymmetry in Obsessive-Compulsive Disorder: Findings From the ENIGMA Consortium.

Journal: Biological psychiatry

Publication Year: 2021

Authors & Co-authors:  Kong Xiang-Zhen XZ Boedhoe Premika S W PSW Abe Yoshinari Y Alonso Pino P Ameis Stephanie H SH Arnold Paul D PD Assogna Francesca F Baker Justin T JT Batistuzzo Marcelo C MC Benedetti Francesco F

No Alterations of Brain Structural Asymmetry in Major Depressive Disorder: An ENIGMA Consortium Analysis.

Journal: The American journal of psychiatry

Publication Year: 2020

Authors & Co-authors:  de Kovel Carolien G F CGF Aftanas Lyubomir L Aleman André A Alexander-Bloch Aaron F AF Baune Bernhard T BT Brack Ivan I Bülow Robin R Busatto Filho Geraldo G Carballedo Angela A Connolly Colm G CG

Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition.

Journal: JAMA psychiatry

Publication Year: 2021

Authors & Co-authors:  van der Meer Dennis D Sønderby Ida E IE Kaufmann Tobias T Walters G Bragi GB Abdellaoui Abdel A Ames David D Amunts Katrin K Andersson Micael M Armstrong Nicola J NJ

ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries.

Journal: Translational psychiatry

Publication Year: 2021

Authors & Co-authors:  Thompson Paul M PM Jahanshad Neda N Ching Christopher R K CRK Salminen Lauren E LE Thomopoulos Sophia I SI Bright Joanna J Baune Bernhard T BT Bertolín Sara S Bralten Janita J Bruin Willem B WB

Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group.

Journal: Molecular psychiatry

Publication Year: 2022

Authors & Co-authors:  Han Laura K M LKM Dinga Richard R Hahn Tim T Ching Christopher R K CRK Eyler Lisa T LT Aftanas Lyubomir L Aghajani Moji M Aleman André A Baune Bernhard T BT Berger Klaus K

Subcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3-90 years.

Journal: Human brain mapping

Publication Year: 2022

Authors & Co-authors:  Dima Danai D Modabbernia Amirhossein A Papachristou Efstathios E Doucet Gaelle E GE Agartz Ingrid I Aghajani Moji M Akudjedu Theophilus N TN Albajes-Eizagirre Anton A Alnaes Dag D Alpert Kathryn I KI

Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3-90 years.

Journal: Human brain mapping

Publication Year: 2022

Authors & Co-authors:  Frangou Sophia S Modabbernia Amirhossein A Williams Steven C R SCR Papachristou Efstathios E Doucet Gaelle E GE Agartz Ingrid I Aghajani Moji M Akudjedu Theophilus N TN Albajes-Eizagirre Anton A Alnaes Dag D

Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs.

Journal: Human brain mapping

Publication Year: 2022

Authors & Co-authors:  Sønderby Ida E IE Ching Christopher R K CRK Thomopoulos Sophia I SI van der Meer Dennis D Sun Daqiang D Villalon-Reina Julio E JE Agartz Ingrid I Amunts Katrin K Arango Celso C Armstrong Nicola J NJ

1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans.

Journal: Translational psychiatry

Publication Year: 2021

Authors & Co-authors:  Sønderby Ida E IE van der Meer Dennis D Moreau Clara C Kaufmann Tobias T Walters G Bragi GB Ellegaard Maria M Abdellaoui Abdel A Ames David D Amunts Katrin K Andersson Micael M

Genetic variants associated with longitudinal changes in brain structure across the lifespan.

Journal: Nature neuroscience

Publication Year: 2022

Authors & Co-authors:  Brouwer Rachel M RM Klein Marieke M Grasby Katrina L KL Schnack Hugo G HG Jahanshad Neda N Teeuw Jalmar J Thomopoulos Sophia I SI Sprooten Emma E Franz Carol E CE Gogtay Nitin N

Event-based modeling in temporal lobe epilepsy demonstrates progressive atrophy from cross-sectional data.

Journal: Epilepsia

Publication Year: 2022

Authors & Co-authors:  Lopez Seymour M SM Aksman Leon M LM Oxtoby Neil P NP Vos Sjoerd B SB Rao Jun J Kaestner Erik E Alhusaini Saud S Alvim Marina M Bender Benjamin B Bernasconi Andrea A

Beyond the Global Brain Differences: Intraindividual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers.

Journal: Biological psychiatry

Publication Year: 2023

Authors & Co-authors:  Boen Rune R Kaufmann Tobias T van der Meer Dennis D Frei Oleksandr O Agartz Ingrid I Ames David D Andersson Micael M Armstrong Nicola J NJ Artiges Eric E Atkins Joshua R JR

Common genetic variants influence human subcortical brain structures.

Journal: Nature

Publication Year: 2015

Authors & Co-authors:  Hibar Derrek P DP Stein Jason L JL Renteria Miguel E ME Arias-Vasquez Alejandro A Desrivières Sylvane S Jahanshad Neda N Toro Roberto R Wittfeld Katharina K Abramovic Lucija L Andersson Micael M

Novel genetic loci underlying human intracranial volume identified through genome-wide association.

Journal: Nature neuroscience

Publication Year: 2017

Authors & Co-authors:  Adams Hieab H H HH Hibar Derrek P DP Chouraki Vincent V Stein Jason L JL Nyquist Paul A PA Rentería Miguel E ME Trompet Stella S Arias-Vasquez Alejandro A Seshadri Sudha S Desrivières Sylvane S

Novel genetic loci associated with hippocampal volume.

Journal: Nature communications

Publication Year: 2018

Authors & Co-authors:  Hibar Derrek P DP Adams Hieab H H HHH Jahanshad Neda N Chauhan Ganesh G Stein Jason L JL Hofer Edith E Renteria Miguel E ME Bis Joshua C JC Arias-Vasquez Alejandro A Ikram M Kamran MK

Genetic architecture of subcortical brain structures in 38,851 individuals.

Journal: Nature genetics

Publication Year: 2020

Authors & Co-authors:  Satizabal Claudia L CL Adams Hieab H H HHH Hibar Derrek P DP White Charles C CC Knol Maria J MJ Stein Jason L JL Scholz Markus M Sargurupremraj Muralidharan M Jahanshad Neda N Roshchupkin Gennady V GV

The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits.

Journal: Twin research and human genetics : the official journal of the International Society for Twin Studies

Publication Year: 2015

Authors & Co-authors:  Silventoinen Karri K Jelenkovic Aline A Sund Reijo R Honda Chika C Aaltonen Sari S Yokoyama Yoshie Y Tarnoki Adam D AD Tarnoki David L DL Ning Feng F Ji Fuling F

Zygosity Differences in Height and Body Mass Index of Twins From Infancy to Old Age: A Study of the CODATwins Project.

Journal: Twin research and human genetics : the official journal of the International Society for Twin Studies

Publication Year: 2016

Authors & Co-authors:  Jelenkovic Aline A Yokoyama Yoshie Y Sund Reijo R Honda Chika C Bogl Leonie H LH Aaltonen Sari S Ji Fuling F Ning Feng F Pang Zengchang Z Ordoñana Juan R JR

Changing genetic architecture of body mass index from infancy to early adulthood: an individual based pooled analysis of 25 twin cohorts.

Journal: International journal of obesity (2005)

Publication Year: 2022

Authors & Co-authors:  Silventoinen Karri K Li Weilong W Jelenkovic Aline A Sund Reijo R Yokoyama Yoshie Y Aaltonen Sari S Piirtola Maarit M Sugawara Masumi M Tanaka Mami M Matsumoto Satoko S