AUTHOR'S PROFILE

Koen Nastassja N

Publications (54)

Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: a meta-analysis of 23 military and civilian cohorts.

Journal: Genome medicine

Publication Year: 2024

Authors & Co-authors:  Katrinli Seyma S Wani Agaz H AH Maihofer Adam X AX Ratanatharathorn Andrew A Daskalakis Nikolaos P NP Montalvo-Ortiz Janitza J Núñez-Ríos Diana L DL Zannas Anthony S AS Zhao Xiang X Aiello Allison E AE

Technical variability across the 450K, EPICv1, and EPICv2 DNA methylation arrays: lessons learned for clinical and longitudinal studies.

Journal: Clinical epigenetics

Publication Year: 2024

Authors & Co-authors:  Lussier Alexandre A AA Schuurmans Isabel K IK Großbach Anna A Maclsaac Julie J Dever Kristy K Koen Nastassja N Zar Heather J HJ Stein Dan J DJ Kobor Michael S MS Dunn Erin C EC

Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts.

Journal: BMC medical genomics

Publication Year: 2024

Authors & Co-authors:  Wani Agaz H AH Katrinli Seyma S Zhao Xiang X Daskalakis Nikolaos P NP Zannas Anthony S AS Aiello Allison E AE Baker Dewleen G DG Boks Marco P MP Brick Leslie A LA Chen Chia-Yen CY

Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts.

Journal: BMC medical genomics

Publication Year: 2024

Authors & Co-authors:  Wani Agaz H AH Katrinli Seyma S Zhao Xiang X Daskalakis Nikolaos P NP Zannas Anthony S AS Aiello Allison E AE Baker Dewleen G DG Boks Marco P MP Brick Leslie A LA Chen Chia-Yen CY

A blended genome and exome sequencing method captures genetic variation in an unbiased, high-quality, and cost-effective manner.

Journal: bioRxiv : the preprint server for biology

Publication Year: 

Authors & Co-authors:  Boltz Toni A TA Chu Benjamin B BB Liao Calwing C Sealock Julia M JM Ye Robert R Majara Lerato L Fu Jack M JM Service Susan S Zhan Lingyu L Medland Sarah E SE

Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: A meta-analysis of 23 military and civilian cohorts.

Journal: medRxiv : the preprint server for health sciences

Publication Year: 

Authors & Co-authors:  Katrinli Seyma S Wani Agaz H AH Maihofer Adam X AX Ratanatharathorn Andrew A Daskalakis Nikolaos P NP Montalvo-Ortiz Janitza J Núñez-Ríos Diana L DL Zannas Anthony S AS Zhao Xiang X Aiello Allison E AE

Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder.

Journal: Nature genetics

Publication Year: 

Authors & Co-authors:  Nievergelt Caroline M CM Maihofer Adam X AX Atkinson Elizabeth G EG Chen Chia-Yen CY Choi Karmel W KW Coleman Jonathan R I JRI Daskalakis Nikolaos P NP Duncan Laramie E LE Polimanti Renato R Aaronson Cindy C

Pharmacotherapy of anxiety disorders: a critical review.

Journal: Dialogues in clinical neuroscience

Publication Year: 2012

Authors & Co-authors:  Koen Nastassja N Stein Dan J DJ

Intimate partner violence: associations with low infant birthweight in a South African birth cohort.

Journal: Metabolic brain disease

Publication Year: 2015

Authors & Co-authors:  Koen Nastassja N Wyatt Gail E GE Williams John K JK Zhang Muyu M Myer Landon L Zar Heather J HJ Stein Dan J DJ

A study of the effects of prenatal alcohol exposure on white matter microstructural integrity at birth.

Journal: Acta neuropsychiatrica

Publication Year: 2016

Authors & Co-authors:  Donald Kirsten Ann KA Roos Annerine A Fouche Jean-Paul JP Koen Nastassja N Howells Fleur M FM Woods Roger P RP Zar Heather J HJ Narr Katherine L KL Stein Dan J DJ

Risk Factors for Antenatal Depression and Associations with Infant Birth Outcomes: Results From a South African Birth Cohort Study.

Journal: Paediatric and perinatal epidemiology

Publication Year: 2016

Authors & Co-authors:  Brittain Kirsty K Myer Landon L Koen Nastassja N Koopowitz Sheri S Donald Kirsten A KA Barnett Whitney W Zar Heather J HJ Stein Dan J DJ

Alcohol exposure in utero is associated with decreased gray matter volume in neonates.

Journal: Metabolic brain disease

Publication Year: 2016

Authors & Co-authors:  Donald Kirsten A KA Fouche J P JP Roos Annerine A Koen Nastassja N Howells Fleur M FM Riley Edward P EP Woods Roger P RP Zar Heather J HJ Narr Katherine L KL Stein Dan J DJ

Interhemispheric Functional Brain Connectivity in Neonates with Prenatal Alcohol Exposure: Preliminary Findings.

Journal: Alcoholism, clinical and experimental research

Publication Year: 2016

Authors & Co-authors:  Donald Kirsten A KA Ipser Jonathan C JC Howells Fleur M FM Roos Annerine A Fouche Jean-Paul JP Riley Edward P EP Koen Nastassja N Woods Roger P RP Biswal Bharat B Zar Heather J HJ

Fronto-temporal alterations and affect regulation in methamphetamine dependence with and without a history of psychosis.

Journal: Psychiatry research. Neuroimaging

Publication Year: 2016

Authors & Co-authors:  Uhlmann Anne A Fouche Jean-Paul JP Koen Nastassja N Meintjes Ernesta M EM Wilson Don D Stein Dan J DJ

White Matter Microstructural Integrity and Neurobehavioral Outcome of HIV-Exposed Uninfected Neonates.

Journal: Medicine

Publication Year: 2016

Authors & Co-authors:  Tran Linh T LT Roos Annerine A Fouche Jean-Paul JP Koen Nastassja N Woods Roger P RP Zar Heather J HJ Narr Katherine L KL Stein Dan J DJ Donald Kirsten A KA

Psychological trauma and posttraumatic stress disorder: risk factors and associations with birth outcomes in the Drakenstein Child Health Study.

Journal: European journal of psychotraumatology

Publication Year: 2016

Authors & Co-authors:  Koen Nastassja N Brittain Kirsty K Donald Kirsten A KA Barnett Whitney W Koopowitz Sheri S Maré Karen K Zar Heather J HJ Stein Dan J DJ

Toward a Global Roadmap for Precision Medicine in Psychiatry: Challenges and Opportunities.

Journal: Omics : a journal of integrative biology

Publication Year: 2017

Authors & Co-authors:  Dalvie Shareefa S Koen Nastassja N McGregor Nathaniel N O'Connell Kevin K Warnich Louise L Ramesar Raj R Nievergelt Caroline M CM Stein Dan J DJ

Maternal posttraumatic stress disorder and infant developmental outcomes in a South African birth cohort study.

Journal: Psychological trauma : theory, research, practice and policy

Publication Year: 2018

Authors & Co-authors:  Koen Nastassja N Brittain Kirsty K Donald Kirsten A KA Barnett Whitney W Koopowitz Sheri S Maré Karen K Zar Heather J HJ Stein Dan J DJ

The developmental effects of HIV and alcohol: a comparison of gestational outcomes among babies from South African communities with high prevalence of HIV and alcohol use.

Journal: AIDS research and therapy

Publication Year: 2018

Authors & Co-authors:  Donald Kirsten A M KAM Fernandez Anne A Claborn Kasey K Kuo Caroline C Koen Nastassja N Zar Heather H Stein Dan J DJ

Investigating tangible and mental resources as predictors of perceived household food insecurity during pregnancy among women in a South African birth cohort study.

Journal: Social science & medicine (1982)

Publication Year: 2018

Authors & Co-authors:  Pellowski Jennifer A JA Barnett Whitney W Kuo Caroline C CC Koen Nastassja N Zar Heather J HJ Stein Dan J DJ

Maternal blood contamination of collected cord blood can be identified using DNA methylation at three CpGs.

Journal: Clinical epigenetics

Publication Year: 2018

Authors & Co-authors:  Morin Alexander M AM Gatev Evan E McEwen Lisa M LM MacIsaac Julia L JL Lin David T S DTS Koen Nastassja N Czamara Darina D Räikkönen Katri K Zar Heather J HJ Koenen Karestan K

Effect of Hazardous Alcohol Use During Pregnancy on Growth Outcomes at Birth: Findings from a South African Cohort Study.

Journal: Alcoholism, clinical and experimental research

Publication Year: 2019

Authors & Co-authors:  Myers Bronwyn B Koen Nastassja N Donald Kirsten A KA Nhapi Raymond T RT Workman Lesley L Barnett Whitney W Hoffman Nadia N Koopowitz Sheri S Zar Heather J HJ Stein Dan J DJ

Gene expression in cord blood links genetic risk for neurodevelopmental disorders with maternal psychological distress and adverse childhood outcomes.

Journal: Brain, behavior, and immunity

Publication Year: 2019

Authors & Co-authors:  Breen Michael S MS Wingo Aliza P AP Koen Nastassja N Donald Kirsten A KA Nicol Mark M Zar Heather J HJ Ressler Kerry J KJ Buxbaum Joseph D JD Stein Dan J DJ

Associations of Emotional, Physical, or Sexual Intimate Partner Violence and Depression Symptoms Among South African Women in a Prospective Cohort Study.

Journal: Journal of interpersonal violence

Publication Year: 2021

Authors & Co-authors:  Okafor Chukwuemeka N CN Barnett Whitney W Zar Heather J HJ Nhapi Raymond R Koen Nastassja N Shoptaw Steve S Stein Dan J DJ

Maltreatment in childhood and intimate partner violence: A latent class growth analysis in a South African pregnancy cohort.

Journal: Child abuse & neglect

Publication Year: 2019

Authors & Co-authors:  Barnett Whitney W Halligan Sarah S Heron Jon J Fraser Abigail A Koen Nastassja N Zar Heather J HJ Donald Kirsty A KA Stein Dan J DJ

Concordance of genetic variation that increases risk for anxiety disorders and posttraumatic stress disorders and that influences their underlying neurocircuitry.

Journal: Journal of affective disorders

Publication Year: 2019

Authors & Co-authors:  van der Merwe Celia C Jahanshad Neda N Cheung Josh W JW Mufford Mary M Groenewold Nynke A NA Koen Nastassja N Ramesar Rajkumar R Dalvie Shareefa S Knowles James A JA

Food-insecure pregnant women in South Africa: a cross-sectional exploration of maternal depression as a mediator of violence and trauma risk factors.

Journal: BMJ open

Publication Year: 2020

Authors & Co-authors:  Barnett Whitney W Pellowski Jennifer J Kuo Caroline C Koen Nastassja N Donald Kirsten A KA Zar Heather J HJ Stein Dan J DJ

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns.

Journal: Nature communications

Publication Year: 2019

Authors & Co-authors:  Czamara Darina D Eraslan Gökçen G Page Christian M CM Lahti Jari J Lahti-Pulkkinen Marius M Hämäläinen Esa E Kajantie Eero E Laivuori Hannele H Villa Pia M PM Reynolds Rebecca M RM

Perinatal depression among mothers in a South African birth cohort study: Trajectories from pregnancy to 18 months postpartum.

Journal: Journal of affective disorders

Publication Year: 2020

Authors & Co-authors:  Pellowski Jennifer A JA Bengtson Angela M AM Barnett Whitney W DiClemente Kira K Koen Nastassja N Zar Heather J HJ Stein Dan J DJ

Risk and protective factors for child development: An observational South African birth cohort.

Journal: PLoS medicine

Publication Year: 2020

Authors & Co-authors:  Donald Kirsten Ann KA Wedderburn Catherine J CJ Barnett Whitney W Nhapi Raymond T RT Rehman Andrea M AM Stadler Jacob A M JAM Hoffman Nadia N Koen Nastassja N Zar Heather J HJ Stein Dan J DJ

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci.

Journal: Nature communications

Publication Year: 2020

Authors & Co-authors:  Nievergelt Caroline M CM Maihofer Adam X AX Klengel Torsten T Atkinson Elizabeth G EG Chen Chia-Yen CY Choi Karmel W KW Coleman Jonathan R I JRI Dalvie Shareefa S Duncan Laramie E LE Gelernter Joel J

Genome-wide Association Studies in Ancestrally Diverse Populations: Opportunities, Methods, Pitfalls, and Recommendations.

Journal: Cell

Publication Year: 2020

Authors & Co-authors:  Peterson Roseann E RE Kuchenbaecker Karoline K Walters Raymond K RK Chen Chia-Yen CY Popejoy Alice B AB Periyasamy Sathish S Lam Max M Iyegbe Conrad C Strawbridge Rona J RJ Brick Leslie L

Maternal health and birth outcomes in a South African birth cohort study.

Journal: PloS one

Publication Year: 2020

Authors & Co-authors:  Zar Heather J HJ Pellowski Jennifer A JA Cohen Sophie S Barnett Whitney W Vanker Aneesa A Koen Nastassja N Stein Dan J DJ

Genetic susceptibility to asthma increases the vulnerability to indoor air pollution.

Journal: The European respiratory journal

Publication Year: 2021

Authors & Co-authors:  Hüls Anke A Vanker Aneesa A Gray Diane D Koen Nastassja N MacIsaac Julia L JL Lin David T S DTS Ramadori Katia E KE Sly Peter D PD Stein Dan J DJ Kobor Michael S MS

A systematic review of research on neuropsychological measures in psychotic disorders from low and middle-income countries: The question of clinical utility.

Journal: Schizophrenia research. Cognition

Publication Year: 

Authors & Co-authors:  Mwesiga Emmanuel K EK Akena Dickens D Koen Nastassja N Senono Richard R Obuku Ekwaro A EA Gumikiriza Joy Louise JL Robbins Reuben N RN Nakasujja Noeline N Stein Dan J DJ

Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation.

Journal: Molecular psychiatry

Publication Year: 2021

Authors & Co-authors:  Sammallahti Sara S Cortes Hidalgo Andrea P AP Tuominen Samuli S Malmberg Anni A Mulder Rosa H RH Brunst Kelly J KJ Alemany Silvia S McBride Nancy S NS Yousefi Paul P Heiss Jonathan A JA

Comparison of antipsychotic naïve first-episode psychosis patients and healthy controls in Uganda.

Journal: Early intervention in psychiatry

Publication Year: 2022

Authors & Co-authors:  Mwesiga Emmanuel K EK Akena Dickens D Koen Nastassja N Nakku Juliet J Nakasujja Noeline N Stein Dan J DJ

The relationship between childhood trauma, socioeconomic status, and maternal depression among pregnant women in a South African birth cohort study.

Journal: SSM - population health

Publication Year: 

Authors & Co-authors:  Mal-Sarkar Tatini T Keyes Katherine K Koen Nastassja N Barnett Whitney W Myer Landon L Rutherford Caroline C Zar Heather J HJ Stein Dan J DJ Lund Crick C

Maternal psychosocial risk factors and child gestational epigenetic age in a South African birth cohort study.

Journal: Translational psychiatry

Publication Year: 2021

Authors & Co-authors:  Koen Nastassja N Jones Meaghan J MJ Nhapi Raymond T RT Lake Marilyn T MT Donald Kirsten A KA Barnett Whitney W Hoffman Nadia N MacIsaac Julia L JL Morin Alexander M AM Lin David T S DTS

Association between maternal depression during pregnancy and newborn DNA methylation.

Journal: Translational psychiatry

Publication Year: 2022

Authors & Co-authors:  Drzymalla Emily E Gladish Nicole N Koen Nastassja N Epstein Michael P MP Kobor Michael S MS Zar Heather J HJ Stein Dan J DJ Hüls Anke A