Augmenting Clinical Interventions in Psychiatric Disorders: Systematic Review and Update on Nutrition.

Journal: Frontiers in psychiatry

Volume: 12

Issue: 

Year of Publication: 

Affiliated Institutions:  Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Uyo, Uyo, Nigeria. Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, University of Port Harcourt, Port Harcourt, Nigeria. Department of Cardiovascular and Endocrine-Metabolic Diseases, and Aging, Istituto Superiore di Sanità, Rome, Italy. Department of Experimental Pharmacology & Toxicology, Faculty of Pharmacy, University of Port Harcourt, Port Harcourt, Nigeria.

Abstract summary 

There is a strong relationship between a healthy diet and mental well-being. Several foods and food compounds are known to modulate biomarkers and molecular mechanisms involved in the aetiogenesis of several mental disorders, and this can be useful in containing the disease progression, including its prophylaxis. This is an updated systematic review of the literature to justify the inclusion and recognition of nutrition in the management of psychiatric illnesses. Such foods and their compounds include dietary flavanols from fruits and vegetables, notable antioxidant and anti-inflammatory agents, probiotics (fermented foods) known to protect good gut bacteria, foods rich in polyunsaturated fatty acids (e.g., Omega-3), and avoiding diets high in saturated fats and refined sugars among others. While the exact mechanism(s) of mitigation of many nutritional interventions are yet to be fully understood, the evidence-based approach warrants the inclusion and co-recognition of nutrition in the management of psychiatric illnesses. For the greater public health benefit, there is a need for policy advocacy aimed at bridging the knowledge gap and encouraging the integration of nutritional intervention with contemporary therapies in clinical settings, as deficiencies of certain nutrients make therapy difficult even with appropriate medication.

Authors & Co-authors:  Offor Samuel J SJ Orish Chinna N CN Frazzoli Chiara C Orisakwe Orish E OE

Study Outcome 

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Statistics
Citations :  WHO, World health Organization . Mental Disorders. (2019). Available online at: https://www.who.int/news-room/fact-sheets/detail/mental-disorders (accessed April 3, 2020).
Authors :  4
Identifiers
Doi : 565583
SSN : 1664-0640
Study Population
Male,Female
Mesh Terms
Other Terms
biomarker;food;mental disorder;microbiome;nutrition;probiotics;psychiatry
Study Design
Cross Sectional Study
Study Approach
Systemic Review
Country of Study
Publication Country
Switzerland