Notes from Beethoven's genome.
Journal: Current biology : CB
Volume: 34
Issue: 6
Year of Publication: 2024
Affiliated Institutions:
Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden; Department of Psychiatry, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands; Department of Cognitive Neuropsychology, Max Planck Institute for Empirical Aesthetics, Frankfurt am Main, Germany. Electronic address: laura.wesseldijk@ki.se.
Music and Health Sciences Research Collaboratory, Faculty of Music, University of Toronto, Toronto, Canada; Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, Canada.
Institute for Logic, Language, and Computation, University of Amsterdam, Amsterdam, The Netherlands.
Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands; Max Planck School of Cognition, Leipzig, Germany.
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Department of Otolaryngology - Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA; Blair School of Music, Vanderbilt University, Nashville, TN, USA; Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA; Department of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.
Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden; Department of Cognitive Neuropsychology, Max Planck Institute for Empirical Aesthetics, Frankfurt am Main, Germany; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Melbourne School of Psychological Sciences, Faculty of Medicine, Dentistry, and Health Sciences, University of Melbourne, CS Melbourne, Australia.
Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden; Department of Cognitive Neuropsychology, Max Planck Institute for Empirical Aesthetics, Frankfurt am Main, Germany.
Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands.
Abstract summary
Rapid advances over the last decade in DNA sequencing and statistical genetics enable us to investigate the genomic makeup of individuals throughout history. In a recent notable study, Begg et al. used Ludwig van Beethoven's hair strands for genome sequencing and explored genetic predispositions for some of his documented medical issues. Given that it was arguably Beethoven's skills as a musician and composer that made him an iconic figure in Western culture, we here extend the approach and apply it to musicality. We use this as an example to illustrate the broader challenges of individual-level genetic predictions.
Authors & Co-authors:
Wesseldijk
Henechowicz
Baker
Bignardi
Karlsson
Gordon
Mosing
Ullén
Fisher
Study Outcome
Source Link: Visit source