The NeuroDev Study: Phenotypic and Genetic Characterization of Neurodevelopmental Disorders in Kenya and South Africa.

Journal: Neuron

Volume: 101

Issue: 1

Year of Publication: 2019

Affiliated Institutions:  Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford OX JX, UK; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Ames Street, Cambridge, MA , USA. Department of Paediatrics & Child Health, (th) Floor ICH Building, Red Cross War Memorial Children's Hospital and University of Cape Town, Rondebosch, South Africa. Neurosciences Unit, Clinical Department, KEMRI-Wellcome Trust Collaborative Research Programme, PO Box -, Kilifi, Kenya. Department of Health Systems and Research Ethics, KEMRI-Wellcome Trust Collaborative Research Programme, Kilifi, Kenya. Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Ames Street, Cambridge, MA , USA; Department of Epidemiology, Harvard School of Public Health, Huntington Avenue, Boston, MA , USA. Department of Medicine, University of Cape Town, Observatory, Cape Town , South Africa. Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford OX JX, UK; Neurosciences Unit, Clinical Department, KEMRI-Wellcome Trust Collaborative Research Programme, PO Box -, Kilifi, Kenya. Department of Psychiatry and Wellcome Centre for Ethics and Humanities, University of Oxford, Oxford, UK. Department of Psychiatry & Mental Health, and MRC Unit on Risk and Resilience in Mental Disorders, University of Cape Town, J-Block, Groote Schuur Hospital, Observatory, Cape Town, South Africa. Neurosciences Unit, Clinical Department, KEMRI-Wellcome Trust Collaborative Research Programme, PO Box -, Kilifi, Kenya. Electronic address: aabubakar@kemri-wellcome.org. Department of Paediatrics & Child Health, (th) Floor ICH Building, Red Cross War Memorial Children's Hospital and University of Cape Town, Rondebosch, South Africa. Electronic address: kirsty.donald@uct.ac.za. Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Ames Street, Cambridge, MA , USA; Department of Epidemiology, Harvard School of Public Health, Huntington Avenue, Boston, MA , USA; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Richard B. Simches Building, (th) Floor, Cambridge Street, Boston, MA , USA. Electronic address: erob@broadinstitute.org.

Abstract summary 

The NeuroDev study will deeply phenotype cognition, behavior, dysmorphias, and neuromedical traits on an expected cohort of 5,600 Africans (1,800 child cases, 1,800 child controls, and 1,900 parents) and will collect whole blood for exome sequencing and biobanking.

Authors & Co-authors:  de Menil Hoogenhout Kipkemoi Kamuya Eastman Galvin Mwangasha de Vries Kariuki Murugasen Mwangi Singh Stein Abubakar Newton Donald Robinson

Study Outcome 

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Statistics
Citations :  Abubakar A, Ssewanyana D, de Vries PJ, and Newton CR (2016). Autism spectrum disorders in sub-Saharan Africa. Lancet Psychiatry 3, 800–802.
Authors :  17
Identifiers
Doi : 10.1016/j.neuron.2018.12.016
SSN : 1097-4199
Study Population
Male,Female
Mesh Terms
Adolescent
Other Terms
Study Design
Study Approach
Country of Study
Kenya
Publication Country
United States